| Size | Price | Stock | Qty |
|---|---|---|---|
| 1mg |
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| Other Sizes |
| Targets |
Trioctyl trimellitate-d6 does not have a biological target; it is a stable isotope-labeled compound used as an analytical standard. The unlabeled compound, trioctyl trimellitate, is a plasticizer that functions as a chemical additive to increase the flexibility of polymers. It does not exert pharmacological effects and is not intended to interact with biological receptors or enzymes.
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|---|---|
| ln Vitro |
In vitro activity is not applicable to Trioctyl trimellitate-d6 as it is an analytical standard rather than a pharmacologically active compound. The compound is characterized by its physicochemical properties, including its deuterium labeling and mass spectrometric behavior. Its utility is demonstrated through its use as an internal standard in quantitative analysis.
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| ln Vivo |
In vivo activity is not applicable to Trioctyl trimellitate-d6. The compound is not administered in vivo for therapeutic purposes. As a plasticizer, trioctyl trimellitate has low toxicity and is not intended for biological activity. The deuterated analog is used exclusively for research and analytical applications.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays are not applicable to Trioctyl trimellitate-d6. The compound is used as an analytical standard for mass spectrometry and chromatography. Standard characterization includes NMR spectroscopy to confirm deuterium incorporation, HPLC or GC to assess purity, and mass spectrometry for molecular weight confirmation.
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| Cell Assay |
In vitro cellular assays are not performed on Trioctyl trimellitate-d6. The compound is used as a chemical standard in analytical method development rather than a biological test agent. Its primary evaluation involves chemical properties such as solubility in organic solvents and stability under storage conditions.
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| Animal Protocol |
In vivo animal studies are not conducted on Trioctyl trimellitate-d6. The compound is a stable isotope-labeled standard used in analytical chemistry. Toxicological and pharmacokinetic studies would be performed on the unlabeled compound, trioctyl trimellitate, which is a widely used plasticizer with established safety data.
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| ADME/Pharmacokinetics |
Pharmacokinetic studies are not performed on Trioctyl trimellitate-d6. The compound is an analytical standard and not a drug candidate. Its physicochemical properties, such as solubility and stability, are characterized for analytical applications. The compound is stored at room temperature and is stable for long periods.
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| Toxicity/Toxicokinetics |
Toxicological studies are not conducted on Trioctyl trimellitate-d6. The unlabeled compound, trioctyl trimellitate, is a plasticizer with low toxicity and is considered safe for use in consumer products. Standard safety precautions for handling chemical standards apply.
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| References | |
| Additional Infomation |
Trioctyl trimellitate-d6 is a deuterium-labeled analog of trioctyl trimellitate (TOTM), a plasticizer. It is used as an internal standard for the quantitation of trioctyl trimellitate in environmental and biological samples using GC-MS or LC-MS/MS. The compound is labeled with six deuterium atoms. This product is for research use only and is not intended for human or veterinary therapeutic use.
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| Molecular Formula |
C33H48D6O6
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|---|---|
| Molecular Weight |
552.82
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| Appearance |
Colorless to light yellow liquid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO :~100 mg/mL (~180.89 mM; with sonication)
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.8089 mL | 9.0445 mL | 18.0891 mL | |
| 5 mM | 0.3618 mL | 1.8089 mL | 3.6178 mL | |
| 10 mM | 0.1809 mL | 0.9045 mL | 1.8089 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
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