| Size | Price | Stock | Qty |
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| 1mg |
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| 5mg |
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| 10mg |
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| Other Sizes |
| Targets |
Not applicable (fluorescent probe; no specific drug target). Dansyl-Gly-Cys-Val-Leu-Ser TFA is a fluorescently labeled peptide used as a probe for studying peptide interactions, enzyme activity, or protein binding. It does not target a specific biological receptor; rather, it is used as a tool for detection and quantification.
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| ln Vitro |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is a dansyl-labeled peptide used as a fluorescent probe. The dansyl fluorophore has excitation and emission maxima suitable for fluorescence detection. The peptide can be used to study peptide-protein interactions, enzyme kinetics, or as a standard for HPLC or mass spectrometry. Detailed biological activity data are not available.
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| ln Vivo |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is not intended for in vivo pharmacological studies; it is used as a fluorescent probe for in vitro biochemical assays. It may be used in animal studies as a tracer or imaging probe, but this is not standard practice.
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| Enzyme Assay |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is used as a fluorescent probe in enzyme assays. For example, it can be used as a substrate for proteases or as a binding probe for proteins. Fluorescence intensity or polarization is measured to assess enzyme activity or binding affinity. The dansyl group enables sensitive detection at nanomolar concentrations.
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| Cell Assay |
Dansyl-Gly-Cys-Val-Leu-Ser TFA can be used in cell-based assays as a fluorescent probe. Cells are treated with the labeled peptide, and fluorescence is measured by flow cytometry, fluorescence microscopy, or fluorescence plate readers. Cellular uptake, localization, or interactions can be studied. Detailed cell-based protocols are not provided in the search results.
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| Animal Protocol |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is not typically used in animal experiments. If used, it would be administered to animals as a tracer or imaging probe, and fluorescence would be detected in tissues or organs. However, this is not standard practice for this compound.
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| ADME/Pharmacokinetics |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is a fluorescent peptide with no pharmacological pharmacokinetic properties. It is soluble in appropriate aqueous buffers and organic solvents. It is typically stored as a powder at -20°C. The compound is stable under recommended storage conditions.
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| Toxicity/Toxicokinetics |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is a research reagent handled with standard laboratory safety practices. It is not intended for in vivo administration. Appropriate personal protective equipment (PPE) should be used when handling the compound. Toxicity data are not available; standard chemical safety precautions apply.
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| References | |
| Additional Infomation |
Dansyl-Gly-Cys-Val-Leu-Ser TFA is a research-grade dansyl-labeled peptide used as a fluorescent probe. Molecular weight: 710.86 (free base). Sequence: {Dansyl}-Gly-Cys-Val-Leu-Ser. The dansyl fluorophore enables fluorescence detection for biochemical assays. For research use only, not for human therapeutic use.
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| Molecular Formula |
C31H46N6O9S2.XC2HF3O2
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| Molecular Weight |
710.86 (free base)
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| Appearance |
White to off-white solid powder
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO :~100 mg/mL (with sonication)
H2O :< 0.1 mg/mL (insoluble) |
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
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