| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
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| Other Sizes |
| Targets |
5-Methoxyresorcinol does not have a specific pharmacological target in the traditional sense, as it is a simple organic compound belonging to the resorcinol class. As a monomethyl ether of phloroglucinol, it may have antioxidant properties. Resorcinol derivatives are known to have various biological activities including antimicrobial and skin-lightening effects. However, specific target information for 5-Methoxyresorcinol is not extensively documented.
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|---|---|
| ln Vitro |
In vitro activity of 5-Methoxyresorcinol (Flamenol) is not extensively documented in the available literature. As a resorcinol derivative, it may exhibit antioxidant activity and potential antimicrobial properties. The compound is primarily used as a research chemical and reference standard. Detailed in vitro activity data, including specific assays and IC50 values, are not available from the search results.
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| ln Vivo |
In vivo activity of 5-Methoxyresorcinol is not extensively documented in the available literature. As a simple organic compound, it is primarily used as a research chemical and reference standard. The compound has been assigned an INN name (Flamenol), indicating some pharmaceutical interest, but detailed in vivo data are not available from the search results.
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| Enzyme Assay |
The in vitro enzyme/receptor binding assay for 5-Methoxyresorcinol is not extensively documented. As a resorcinol derivative, antioxidant assays such as DPPH or ABTS radical scavenging assays may be performed to evaluate its activity. Standard protocols include incubation of the compound with the radical-generating system and spectrophotometric measurement of radical reduction. Appropriate positive controls such as ascorbic acid or Trolox are included.
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| Cell Assay |
In vitro cell-based assays for 5-Methoxyresorcinol are not extensively documented in the available literature. As a research chemical, it may be used in cell culture studies to evaluate its effects on melanin production, antioxidant activity, or other biological endpoints. Standard protocols include treatment of cells with the compound at various concentrations and measurement of relevant endpoints using appropriate assays.
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| Animal Protocol |
In vivo animal studies for 5-Methoxyresorcinol are not extensively documented in the available literature. As a research chemical, it may be used in animal models for specific research applications. Detailed in vivo protocols and efficacy data are not available from the search results. The compound is intended for research use only.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of 5-Methoxyresorcinol include a molecular weight of 140.138 g/mol and formula C7H8O3. It has CAS number 2174-64-3. The compound has a UNII identifier of 6201E0JIF3. Detailed pharmacokinetic parameters such as solubility, half-life, and bioavailability are not extensively documented in the available literature. The compound is intended for research use only.
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| Toxicity/Toxicokinetics |
Toxicity information for 5-Methoxyresorcinol is limited. As a research chemical, standard safety precautions for handling should be followed. The compound is designated for research use only and is not for human therapeutic applications. No detailed toxicity data are available from the search results.
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| References | |
| Additional Infomation |
Flamenol is a type of resorcinol compound with a structure similar to phloroglucinol, except that one of its phenolic hydroxyl hydrogen atoms is replaced by a methyl group. It is a metabolite of rapeseed. Flamenol belongs to the resorcinol class and is also a monomethoxybenzene. Functionally, it is related to phloroglucinol.
5-Methoxyresorcinol (Flamenol) is a monomethyl ether of phloroglucinol belonging to the resorcinol class. It has MW 140.138 and formula C7H8O3. CAS 2174-64-3 and UNII 6201E0JIF3. It is also known as 3,5-dihydroxyanisole. It is intended for research use only. |
| Molecular Formula |
C7H8O3
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|---|---|
| Molecular Weight |
140.14
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| Exact Mass |
140.047
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| CAS # |
2174-64-3
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| PubChem CID |
71648
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| Appearance |
Off-white to yellow solid powder
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| Density |
1.3±0.1 g/cm3
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| Boiling Point |
326.4±0.0 °C at 760 mmHg
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| Melting Point |
78-80 °C(lit.)
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| Flash Point |
122.5±19.0 °C
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| Vapour Pressure |
0.0±0.7 mmHg at 25°C
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| Index of Refraction |
1.580
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| LogP |
0.91
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| Hydrogen Bond Donor Count |
2
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| Hydrogen Bond Acceptor Count |
3
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
10
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| Complexity |
95
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| Defined Atom Stereocenter Count |
0
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| SMILES |
COC1=CC(=CC(=C1)O)O
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| InChi Key |
HDVRLUFGYQYLFJ-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C7H8O3/c1-10-7-3-5(8)2-6(9)4-7/h2-4,8-9H,1H3
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| Chemical Name |
5-methoxybenzene-1,3-diol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
Typically soluble in DMSO (e.g. 10 mM)
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.1357 mL | 35.6786 mL | 71.3572 mL | |
| 5 mM | 1.4271 mL | 7.1357 mL | 14.2714 mL | |
| 10 mM | 0.7136 mL | 3.5679 mL | 7.1357 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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