| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
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| 1g |
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| 5g |
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| Targets |
2-Chloromethyl-4-methoxy-3-methylpyridine does not have a specific biological target. It is a chemical building block used in organic synthesis and pharmaceutical research. Its primary use is as an intermediate for the synthesis of more complex molecules, particularly proton pump inhibitors.
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|---|---|
| ln Vitro |
Specific in vitro activity data for 2-Chloromethyl-4-methoxy-3-methylpyridine are not detailed in the search results. As a chemical intermediate, its biological activity is not typically the focus of research, but rather its utility in synthesizing other compounds.
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| ln Vivo |
Specific in vivo activity data for 2-Chloromethyl-4-methoxy-3-methylpyridine are not detailed in the search results. It is not a drug or a biologically active compound itself.
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| Enzyme Assay |
Non-cellular assays for 2-Chloromethyl-4-methoxy-3-methylpyridine are not performed, as it is a chemical intermediate. Its purity and identity can be confirmed by analytical techniques such as HPLC, NMR, and mass spectrometry.
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| Cell Assay |
In vitro cellular assays for 2-Chloromethyl-4-methoxy-3-methylpyridine are not typically performed, as it is a chemical intermediate rather than a biologically active compound.
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| Animal Protocol |
In vivo animal experiments for 2-Chloromethyl-4-methoxy-3-methylpyridine are not conducted, as it is not a drug or a biologically active compound.
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| ADME/Pharmacokinetics |
2-Chloromethyl-4-methoxy-3-methylpyridine has a molecular formula of C8H10ClNO and a molecular weight of 171.62. Its CAS number is 124473-12-7. It is a light yellow liquid with a purity of 95%. It is also known as 2-(chloromethyl)-4-methoxy-3-methylpyridine.
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| Toxicity/Toxicokinetics |
Toxicological data for 2-Chloromethyl-4-methoxy-3-methylpyridine are not detailed in the search results. As a chemical intermediate, standard safety precautions for handling organic compounds should be followed.
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| Additional Infomation |
2-Chloromethyl-4-methoxy-3-methylpyridine is a pyridine derivative used in organic synthesis. It is often used in pharmaceutical applications due to its potential biological activity. It is a chemical intermediate, not a drug.
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| Molecular Weight |
208.09
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|---|---|
| Exact Mass |
207.021
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| CAS # |
124473-12-7
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| PubChem CID |
10725857
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.139g/cm3
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| Boiling Point |
257.508ºC at 760 mmHg
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| Flash Point |
109.537ºC
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| Vapour Pressure |
0.023mmHg at 25°C
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| Index of Refraction |
1.518
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| LogP |
2.939
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
11
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| Complexity |
121
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CC1=C(CCl)N=CC=C1OC
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| InChi Key |
UIRCDHHEYPUZGA-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C8H10ClNO/c1-6-7(5-9)10-4-3-8(6)11-2/h3-4H,5H2,1-2H3
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| Chemical Name |
2-(chloromethyl)-4-methoxy-3-methylpyridine
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.8056 mL | 24.0281 mL | 48.0561 mL | |
| 5 mM | 0.9611 mL | 4.8056 mL | 9.6112 mL | |
| 10 mM | 0.4806 mL | 2.4028 mL | 4.8056 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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