| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
Human Endogenous Metabolite
Zinc Phytate targets metal ion chelation and mineral absorption. As a zinc salt of phytic acid, it is involved in mineral binding and may affect the bioavailability of minerals such as zinc, iron, and calcium. Its "target" in research is the study of mineral metabolism, nutrition absorption, and antioxidant defense. |
|---|---|
| ln Vitro |
In vitro, Zinc Phytate is used to study mineral chelation, antioxidant activity, and nutrition absorption. It is a zinc salt of phytic acid with the ability to chelate metal ions. Its activity is measured by assessing metal ion binding, antioxidant capacity, and effects on mineral bioavailability in cell-free systems.
|
| ln Vivo |
In vivo, Zinc Phytate is found in food and is important for human nutrition absorption. It is used as a food additive and dietary supplement. It may have health benefits including antioxidant properties. It is not a therapeutic agent but is studied in the context of nutrition and metabolism.
|
| Enzyme Assay |
In vitro enzyme assays with Zinc Phytate typically involve studying its effects on enzymes involved in mineral metabolism or antioxidant defense. The compound can be used to assess its metal chelation properties and antioxidant activity. Standard assays involve incubating zinc phytate with enzyme preparations or metal ions and measuring activity by spectrophotometric or chromatographic methods.
|
| Cell Assay |
Zinc Phytate is not typically used in cell culture experiments as a bioactive compound for treating cells. However, it may be employed in studies investigating mineral metabolism, antioxidant defense, or nutrition absorption. Cells are treated with zinc phytate, and endpoints include assessment of metal ion uptake, oxidative stress markers, and cell viability.
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| Animal Protocol |
In vivo animal experiments with Zinc Phytate typically involve administering the compound via dietary incorporation to study its effects on mineral absorption, antioxidant status, and nutrition. Key endpoints include assessment of mineral levels in blood and tissues, oxidative stress markers, and metabolic parameters. These studies evaluate the nutritional and health effects of zinc phytate.
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| ADME/Pharmacokinetics |
The pharmacokinetic (PK) properties of Zinc Phytate reflect its role as a dietary component. As a large, polar molecule (molecular weight 1040.28), it is not significantly absorbed in the gastrointestinal tract. It acts locally in the gut to chelate metal ions and may affect mineral bioavailability. It appears as a white powder.
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| Toxicity/Toxicokinetics |
Zinc Phytate has a low toxicity profile as a naturally occurring food component. It is generally recognized as safe for use as a food additive and dietary supplement. For research use, standard laboratory safety practices are sufficient. It is not classified as a hazardous substance.
|
| References | |
| Additional Infomation |
Zinc Phytate is the zinc salt of phytic acid, a compound found in food and important for human nutrition absorption. It is commonly used as a food additive and dietary supplement due to its ability to chelate metal ions and its potential health benefits, including antioxidant properties. The compound is not a drug and has no therapeutic indications. It is available for research use.
|
| Molecular Formula |
C6H6O24P6ZN6
|
|---|---|
| Molecular Weight |
1040.22
|
| Exact Mass |
1031.342
|
| CAS # |
63903-51-5
|
| Related CAS # |
Phytic acid;83-86-3
|
| PubChem CID |
498066
|
| Appearance |
White to off-white solid powder
|
| Density |
2.42g/cm3
|
| Boiling Point |
1190.7ºC at 760 mmHg
|
| Flash Point |
673.9ºC
|
| LogP |
2.11
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
24
|
| Rotatable Bond Count |
6
|
| Heavy Atom Count |
42
|
| Complexity |
749
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
C1(C(C(C(C(C1OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-].[Zn+2].[Zn+2].[Zn+2].[Zn+2].[Zn+2].[Zn+2]
|
| InChi Key |
WYGJAFDJPBTRSB-UHFFFAOYSA-B
|
| InChi Code |
InChI=1S/C6H18O24P6.6Zn/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;/q;6*+2/p-12
|
| Chemical Name |
hexazinc;(2,3,4,5,6-pentaphosphonatooxycyclohexyl) phosphate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
10%TFA: 50 mg/mL (48.07 mM)
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.9613 mL | 4.8067 mL | 9.6134 mL | |
| 5 mM | 0.1923 mL | 0.9613 mL | 1.9227 mL | |
| 10 mM | 0.0961 mL | 0.4807 mL | 0.9613 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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