| Size | Price | Stock | Qty |
|---|---|---|---|
| 250mg |
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| Other Sizes |
| Targets |
Bathocuproine disulfonate disodium does not have a defined pharmacological target. It is a chelating agent used for the colorimetric detection of copper(I) ions. Its mechanism of action is chemical: it forms a stable complex with Cu⁺ ions, producing a color change that can be measured spectrophotometrically.
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|---|---|
| ln Vitro |
A biochemical reagent called disodium bathocuproine disulfonate can be utilized in life science research as an organic compound or biological material.
In vitro, bathocuproine disulfonate disodium is used as a colorimetric reagent for the detection and quantification of copper ions. It is used in biochemical assays to measure copper concentration in biological samples and to study copper metabolism and copper-related diseases. |
| ln Vivo |
In vivo data for bathocuproine disulfonate disodium as a therapeutic agent are not available, as the compound is a chemical reagent used for in vitro analytical applications. It is not intended for in vivo administration and has no established in vivo pharmacokinetic or pharmacodynamic profile.
|
| Enzyme Assay |
For in vitro copper detection assays, bathocuproine disulfonate disodium is used as a colorimetric reagent. Standard protocols involve dissolving the compound in an appropriate buffer and adding it to samples containing copper ions. The formation of the colored Cu⁺-bathocuproine complex is measured spectrophotometrically at a specific wavelength (e.g., 480 nm).
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| Cell Assay |
For in vitro cell-based experiments, bathocuproine disulfonate disodium is not typically used directly in cell culture. It is a chemical reagent used for analytical applications. The compound may be used in the analysis of cell culture samples to measure copper content, but it is not added directly to cell cultures as a test compound.
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| Animal Protocol |
In vivo animal studies for bathocuproine disulfonate disodium are not applicable, as the compound is a chemical reagent used for in vitro applications. No animal studies have been conducted for this compound as a therapeutic agent.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of bathocuproine disulfonate disodium are not available, as the compound is not a drug and is not administered to living organisms. The compound is a solid and should be stored under appropriate conditions.
|
| Toxicity/Toxicokinetics |
Bathocuproine disulfonate disodium is a research chemical and should be handled with appropriate laboratory safety precautions. As a sulfonated compound, it may cause skin and eye irritation. The compound is for research use only and not for human therapeutic or diagnostic applications.
|
| Additional Infomation |
See other relationships...
Bathocuproine disulfonate disodium (CAS 52698-84-7) is primarily a research-grade chemical reagent, not an FDA-approved pharmaceutical drug. Its primary application is as a colorimetric reagent for the detection and quantification of copper(I) ions in biochemical research. |
| Molecular Formula |
C26H18N2NA2O6S2
|
|---|---|
| Molecular Weight |
564.54
|
| Exact Mass |
564.04
|
| CAS # |
52698-84-7
|
| PubChem CID |
15678335
|
| Appearance |
Off-white to light brown solid powder
|
| Melting Point |
300ºC
|
| LogP |
6.703
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
8
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
38
|
| Complexity |
874
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CC1=C(C(=C2C=CC3=C(C(=C(N=C3C2=N1)C)S(=O)(=O)[O-])C4=CC=CC=C4)C5=CC=CC=C5)S(=O)(=O)[O-].[Na+].[Na+]
|
| InChi Key |
RNGKZLRAVYPLJC-UHFFFAOYSA-L
|
| InChi Code |
InChI=1S/C26H20N2O6S2.2Na/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2
|
| Chemical Name |
disodium;2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage. (2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O: 50 mg/mL (88.57 mM)
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.7714 mL | 8.8568 mL | 17.7135 mL | |
| 5 mM | 0.3543 mL | 1.7714 mL | 3.5427 mL | |
| 10 mM | 0.1771 mL | 0.8857 mL | 1.7714 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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