![Fluorol Yellow 088 (2,8-Dimethylnaphtho[3,2,1-kl]xanthene)](/upload/1124/V68648.png)
| Size | Price | Stock | Qty |
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| 250mg |
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| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
Fluorol Yellow 088 does not have a specific biological target. It is a fluorescent dye used for staining lipids in plant tissues. The compound binds to hydrophobic structures such as suberized cell walls and lipid-containing cellular components, enabling their visualization by fluorescence microscopy. It does not have pharmacological activity and is not used as a therapeutic agent.
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| ln Vitro |
In vitro, Fluorol Yellow 088 is used as a fluorescent dye for lipid staining in plant tissues. It is particularly efficient for staining suberized cell walls and hydrophobic structures. The compound is not used in mammalian cell culture or in assays of biological activity. Its primary application is in plant biology research for imaging and histochemical analysis.
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| ln Vivo |
In vivo data for Fluorol Yellow 088 are limited as it is a fluorescent dye used primarily for ex vivo staining of plant tissues. The compound is not administered to animals and is not used in in vivo imaging applications in mammals. Its use is restricted to plant biology research and fluorescence microscopy.
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| Enzyme Assay |
Fluorol Yellow 088 is not used in cell-free enzyme/receptor binding assays. Its role in research is as a fluorescent dye for lipid staining. The compound is applied to plant tissue sections or whole mounts, and its fluorescence is visualized by microscopy. No biochemical assays involving enzymes or receptors are performed with this compound.
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| Cell Assay |
Cell-based assays are not performed with Fluorol Yellow 088 in mammalian cell culture. The compound is used for staining plant tissues, particularly suberized cell walls and hydrophobic structures. Plant tissue sections are incubated with the dye, washed, and examined under a fluorescence microscope. The dye's fluorescence allows visualization of lipid-rich structures.
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| Animal Protocol |
In vivo animal studies are not conducted with Fluorol Yellow 088. The compound is not a drug candidate and is not administered to animals. Its applications are limited to plant biology research and ex vivo tissue staining.
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| ADME/Pharmacokinetics |
Fluorol Yellow 088 is a synthetic fluorescent dye and is not subject to pharmacokinetic evaluation as a drug. Its physicochemical properties include a molecular weight of 296.36 g/mol and a molecular formula of C22H16O. The compound is stable under normal storage conditions and is soluble in organic solvents. Its fluorescence properties make it suitable for microscopy applications.
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| Toxicity/Toxicokinetics |
The toxicological profile of Fluorol Yellow 088 has not been extensively characterized. As a fluorescent dye, it may pose health hazards if ingested, inhaled, or upon skin contact. Standard laboratory safety precautions should be observed, including the use of personal protective equipment (gloves, goggles, lab coat) and adequate ventilation.
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| Additional Infomation |
See also: CI Solvent Green 4 (note moved to).
Fluorol Yellow 088 is not a drug but a fluorescent dye used for lipid staining in plant biology research. It is particularly efficient for staining suberized cell walls and hydrophobic structures. The compound is used as a biochemical reagent for biomedical research. It is not approved for clinical use and is intended for research purposes only. |
| Molecular Formula |
C22H16O
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|---|---|
| Molecular Weight |
296.36
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| Exact Mass |
296.12
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| CAS # |
81-37-8
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| PubChem CID |
5052385
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| Appearance |
Yellow to brown solid powder
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| Density |
1.234g/cm3
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| Boiling Point |
512.5ºC at 760 mmHg
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| Flash Point |
265.9ºC
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| Index of Refraction |
1.732
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| LogP |
6.382
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
0
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| Heavy Atom Count |
23
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| Complexity |
445
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CC1=CC2=C(C=C1)OC3=CC=C(C4=CC5=CC=CC=C5C2=C34)C
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| InChi Key |
WYVHNCGXVPMYQK-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C22H16O/c1-13-7-9-19-18(11-13)21-16-6-4-3-5-15(16)12-17-14(2)8-10-20(23-19)22(17)21/h3-12H,1-2H3
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| Chemical Name |
4,12-dimethyl-8-oxapentacyclo[11.7.1.02,7.09,21.015,20]henicosa-1(21),2(7),3,5,9,11,13,15,17,19-decaene
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage. (2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: 4 mg/mL (13.50 mM)
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.3743 mL | 16.8714 mL | 33.7427 mL | |
| 5 mM | 0.6749 mL | 3.3743 mL | 6.7485 mL | |
| 10 mM | 0.3374 mL | 1.6871 mL | 3.3743 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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