| Size | Price | Stock | Qty |
|---|---|---|---|
| 100g |
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| Other Sizes |
| Targets |
Ethyl 2-(dimethylamino)acetate is not a pharmacological agent with a defined biological target. Its primary role is as a synthetic intermediate and organic compound. The compound is a glycine analogue and can be explored for its potential applications in areas such as neurology, metabolism, and drug discovery.
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|---|---|
| ln Vitro |
Commercial ergot supplements have been made from amino acids and their derivatives. They affect the release of anabolic hormones, the availability of fuel for activity, the ability to think clearly under pressure, and the prevention of muscular damage brought on by exertion. They are regarded as advantageous synergistic food ingredients [1].
The in vitro activity of Ethyl 2-(dimethylamino)acetate is evaluated through its performance as a synthetic intermediate. The compound is an organic compound consisting of an ethyl ester group attached to a dimethylamino group at the α-position of acetate. It can be explored for its potential applications in various research areas. |
| ln Vivo |
In vivo activity is not applicable.
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| Enzyme Assay |
The in vitro enzyme/receptor binding (non-cellular) experimental workflow involves standard organic synthesis procedures. The compound is a glycine analogue. The compound has a molecular formula of C₆H₁₃NO₂.
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| Cell Assay |
In vitro cell-based experimental workflows are not typically performed.
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| Animal Protocol |
In vivo animal experiments are not applicable.
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| ADME/Pharmacokinetics |
The pharmacokinetic properties have not been characterized.
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| Toxicity/Toxicokinetics |
The toxicological data indicate the compound is flammable. It is incompatible with strong oxidizing agents. Standard laboratory safety practices should be followed.
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| References |
[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
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| Additional Infomation |
Ethyl 2-(dimethylamino)acetate is a glycine analogue. The compound can be explored for its potential applications in areas such as neurology, metabolism, and drug discovery. The compound is not a drug and has no clinical trials or approvals. The compound is for research use only. The compound is available from multiple suppliers. The compound has synonyms including N,N-dimethylglycine ethyl ester.
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| Molecular Formula |
C6H13NO2
|
|---|---|
| Molecular Weight |
131.18
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| Exact Mass |
131.094
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| CAS # |
33229-89-9
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| PubChem CID |
118412
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| Appearance |
Colorless to light yellow liquid（Density：0.928 g/cm3）
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| Density |
0.9±0.1 g/cm3
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| Boiling Point |
150.5±0.0 °C at 760 mmHg
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| Flash Point |
44.4±0.0 °C
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| Vapour Pressure |
3.8±0.2 mmHg at 25°C
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| Index of Refraction |
1.425
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| LogP |
0.69
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| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
4
|
| Heavy Atom Count |
9
|
| Complexity |
91.1
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| Defined Atom Stereocenter Count |
0
|
| SMILES |
CCOC(=O)CN(C)C
|
| InChi Key |
BGCNBOFPABQGNG-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C6H13NO2/c1-4-9-6(8)5-7(2)3/h4-5H2,1-3H3
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| Chemical Name |
ethyl 2-(dimethylamino)acetate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.6231 mL | 38.1156 mL | 76.2311 mL | |
| 5 mM | 1.5246 mL | 7.6231 mL | 15.2462 mL | |
| 10 mM | 0.7623 mL | 3.8116 mL | 7.6231 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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