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| Other Sizes |
| Targets |
Methyl undec-10-enoate does not target a specific protein or enzyme in biological systems. As a fatty acid methyl ester, its utility is based on its chemical properties rather than pharmacological target engagement. The terminal alkene group provides a reactive site for various chemical transformations, including epoxidation, hydrogenation, and polymerization. In biological contexts, the compound may be metabolized by esterases to release the corresponding fatty acid, which could then participate in lipid metabolism pathways. However, this is not a specific receptor-mediated interaction but rather general metabolic processing.
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| ln Vitro |
Methyl undec-10-enoate is a biochemical reagent that can be utilized in research pertaining to life sciences as an organic compound or biological material.
The in vitro activity of methyl undec-10-enoate is primarily related to its function as a chemical reagent and biochemical research tool. The compound is used as a biological material or organic compound for life science related research. Its terminal alkene group makes it useful for studying reactions involving alkenes, including addition reactions and polymerization. The methyl ester can be hydrolyzed to the corresponding acid, which is a valuable intermediate for the synthesis of various bioactive compounds. The compound may also be used in studies of lipid metabolism and fatty acid transport. |
| ln Vivo |
No significant in vivo activity has been reported for methyl undec-10-enoate as a therapeutic agent. The compound is primarily utilized as a research reagent and chemical intermediate rather than a pharmacologically active compound. If administered systemically, the compound would likely be metabolized by esterases to undec-10-enoic acid, which could then enter fatty acid oxidation pathways. However, no specific pharmacological effects have been documented.
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| Enzyme Assay |
In vitro enzyme assays for methyl undec-10-enoate are not typically performed, as the compound is not a substrate for specific enzymes in the same way that chromogenic or fluorogenic substrates are. However, esterase activity could be measured by monitoring the hydrolysis of the methyl ester to the corresponding acid. The compound could also be used in studies of lipid metabolism to examine the uptake and utilization of fatty acid esters by cells.
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| Cell Assay |
For in vitro cellular experiments, methyl undec-10-enoate can be dissolved in organic solvents and diluted in cell culture medium. It may be used to study the effects of fatty acid esters on cellular metabolism, lipid accumulation, or membrane properties. The compound could also be used as a precursor for the synthesis of labeled or functionalized lipids for cellular imaging or tracking studies. However, specific protocols are not well-documented in the literature.
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| Animal Protocol |
In vivo animal experiments with methyl undec-10-enoate are not commonly performed, as the compound is primarily used as a research reagent and chemical intermediate. If used in animal studies, it would most likely be as a precursor for the synthesis of other compounds or as a model compound for studying fatty acid ester metabolism.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of methyl undec-10-enoate have not been characterized, as the compound is a research-use chemical reagent rather than a drug candidate. The compound has a molecular weight of 198.30 g/mol and is a liquid at room temperature. If absorbed, it would likely be metabolized by esterases to undec-10-enoic acid and methanol.
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| Toxicity/Toxicokinetics |
Toxicological data for methyl undec-10-enoate has not been systematically evaluated, as the compound is intended for research applications only and not for therapeutic use. Standard laboratory safety precautions should be observed when handling this chemical reagent, including the use of appropriate personal protective equipment.
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| Additional Infomation |
Methyl undecenoate is a fatty acid methyl ester of 10-undecenoic acid, a metabolite whose function is related to 10-undecenoic acid. Methyl undecenoate has been reported to have been found in yarrow (Achillea millefolium), and relevant data are available for reference.
Methyl undec-10-enoate (CAS# 111-81-9) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also known as methyl 10-undecenoate and methyl undecylenate. The compound serves as a valuable intermediate in organic synthesis due to its terminal alkene and ester functional groups. It has no clinical or therapeutic applications and has not received regulatory approval for any medical indication. |
| Molecular Formula |
C12H22O2
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|---|---|
| Molecular Weight |
198.30
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| Exact Mass |
198.161
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| CAS # |
111-81-9
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| PubChem CID |
8138
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| Appearance |
Colorless to light yellow liquid
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| Density |
0.9±0.1 g/cm3
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| Boiling Point |
247.3±9.0 °C at 760 mmHg
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| Melting Point |
27.5 °C
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| Flash Point |
99.3±14.5 °C
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| Vapour Pressure |
0.0±0.5 mmHg at 25°C
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| Index of Refraction |
1.438
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| LogP |
4.45
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
10
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| Heavy Atom Count |
14
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| Complexity |
152
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C=CCCCCCCCCC(=O)OC
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| InChi Key |
KISVAASFGZJBCY-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C12H22O2/c1-3-4-5-6-7-8-9-10-11-12(13)14-2/h3H,1,4-11H2,2H3
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| Chemical Name |
methyl undec-10-enoate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.0429 mL | 25.2143 mL | 50.4286 mL | |
| 5 mM | 1.0086 mL | 5.0429 mL | 10.0857 mL | |
| 10 mM | 0.5043 mL | 2.5214 mL | 5.0429 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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