| Size | Price | Stock | Qty |
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| 100mg |
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| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
Dodecyl β-D-glucopyranoside does not target a specific protein or enzyme for pharmacological intervention. Its utility is as a non-ionic detergent and surfactant for biochemical research. The compound increases chloramphenicol acetyltransferase (CAT) activity when used at a concentration of 204 µM.
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| ln Vitro |
The in vitro activity of Dodecyl β-D-glucopyranoside is its function as a non-ionic detergent and surfactant. The compound is used in detergent and colloid research and micelle development. It has a critical micelle concentration (CMC) of 190 µM and increases chloramphenicol acetyltransferase (CAT) activity at 204 µM.
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| ln Vivo |
No significant in vivo activity has been reported for Dodecyl β-D-glucopyranoside as a therapeutic agent. The compound is primarily utilized as a biochemical reagent and surfactant rather than a pharmacologically active compound.
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| Enzyme Assay |
In vitro assays for Dodecyl β-D-glucopyranoside involve its use as a non-ionic detergent for protein solubilization and membrane studies. The compound is used in detergent and colloid research and micelle development.
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| Cell Assay |
For in vitro cellular experiments, Dodecyl β-D-glucopyranoside is not typically used in live cell assays. The compound is used in biochemical assays as a detergent for protein extraction and solubilization.
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| Animal Protocol |
In vivo animal experiments with Dodecyl β-D-glucopyranoside are not commonly performed, as the compound is primarily used as a biochemical reagent rather than a therapeutic candidate.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of Dodecyl β-D-glucopyranoside have not been characterized, as it is a research-use biochemical reagent rather than a drug candidate. The compound has a molecular weight of 348.48 g/mol and a CMC of 190 µM. It should be stored under appropriate conditions.
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| Toxicity/Toxicokinetics |
The compound is intended for research use only and not for human therapeutic or diagnostic applications. Standard laboratory safety precautions should be observed when handling this chemical reagent.
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| References | |
| Additional Infomation |
See also: lauryl glucoside (note moved to).
Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant used in detergent and colloid research, micelle development, and as a biochemical reagent. The compound has no clinical or therapeutic applications. |
| Molecular Formula |
C18H36O6
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|---|---|
| Exact Mass |
348.251
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| CAS # |
59122-55-3
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| PubChem CID |
93321
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.1±0.1 g/cm3
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| Boiling Point |
499.1±45.0 °C at 760 mmHg
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| Flash Point |
255.6±28.7 °C
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| Vapour Pressure |
0.0±2.9 mmHg at 25°C
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| Index of Refraction |
1.509
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| LogP |
3.15
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| Hydrogen Bond Donor Count |
4
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| Hydrogen Bond Acceptor Count |
6
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| Rotatable Bond Count |
13
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| Heavy Atom Count |
24
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| Complexity |
301
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| Defined Atom Stereocenter Count |
5
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| SMILES |
O1[C@]([H])([C@@]([H])([C@]([H])([C@@]([H])([C@@]1([H])C([H])([H])O[H])O[H])O[H])O[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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| InChi Key |
PYIDGJJWBIBVIA-UYTYNIKBSA-N
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| InChi Code |
InChI=1S/C18H36O6/c1-2-3-4-5-6-7-8-9-10-11-12-23-18-17(22)16(21)15(20)14(13-19)24-18/h14-22H,2-13H2,1H3/t14-,15-,16+,17-,18-/m1/s1
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| Chemical Name |
(2R,3R,4S,5S,6R)-2-dodecoxy-6-(hydroxymethyl)oxane-3,4,5-triol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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