| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
Silver diethyldithiocarbamate does not target a specific protein or enzyme for pharmacological intervention. Its utility is as a chemical reagent and analytical tool. The compound serves as a copper chelator and is utilized to quantitate copper in biological materials by ESR. It is also used in the colorimetric determination of arsenic.
|
|---|---|
| ln Vitro |
A biochemical reagent called silver diethyldithiocarbamate can be utilized in life science research as an organic compound or biological substance.
The in vitro activity of Silver diethyldithiocarbamate includes its function as a colorimetric reagent for arsenic determination and as a copper chelator. It exhibits properties associated with both silver and dithiocarbamate functionalities, including potential antimicrobial and antifungal activities. The compound can be employed in the synthesis of silver nanoparticles and as a precursor in various chemical reactions. It plays a useful role in the deposition of acanthite (Ag₂S) thin films for photoelectrochemical applications. |
| ln Vivo |
Silver diethyldithiocarbamate is not used as a therapeutic agent. Its in vivo utility is limited to research applications as an analytical reagent. The compound is not intended for systemic therapeutic use.
|
| Enzyme Assay |
In vitro assays for Silver diethyldithiocarbamate involve its use as a colorimetric reagent for the determination of arsenic. The compound is incubated with samples containing arsenic, and the resulting color change is measured spectrophotometrically. It is also used to develop ion-selective electrodes for nitrate ion detection.
|
| Cell Assay |
For in vitro cellular experiments, Silver diethyldithiocarbamate is not typically used in cell-based assays. The compound is primarily used as an analytical reagent and in materials science applications.
|
| Animal Protocol |
In vivo animal experiments with Silver diethyldithiocarbamate are not commonly performed, as the compound is primarily used as a chemical reagent rather than a therapeutic candidate.
|
| ADME/Pharmacokinetics |
Pharmacokinetic properties of Silver diethyldithiocarbamate have not been characterized, as it is a research-use chemical reagent rather than a drug candidate. The compound has a molecular weight of 256.13 g/mol and should be stored under appropriate conditions.
|
| Toxicity/Toxicokinetics |
Silver compounds can be toxic, and appropriate handling and disposal methods should be followed. The compound is intended for research use only and not for human therapeutic or diagnostic applications. Standard laboratory safety precautions should be observed when handling this chemical reagent.
|
| Additional Infomation |
Silver diethyldithiocarbamate is an organosilver compound used as a colorimetric reagent for arsenic determination, a copper chelator, and a precursor for silver nanoparticle synthesis. The compound has no clinical or therapeutic applications and has not received regulatory approval for any medical indication.
|
| Molecular Formula |
C5H10AGNS2
|
|---|---|
| Molecular Weight |
256.14
|
| Exact Mass |
254.93
|
| CAS # |
1470-61-7
|
| PubChem CID |
3034078
|
| Appearance |
Light yellow to light brown solid powder
|
| Boiling Point |
176.4ºC at 760 mmHg
|
| Melting Point |
172-175 °C(lit.)
|
| Flash Point |
60.5ºC
|
| LogP |
1.81
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
2
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
9
|
| Complexity |
73
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CCN(CC)C(=S)[S-].[Ag+]
|
| InChi Key |
NSVHDIYWJVLAGH-UHFFFAOYSA-M
|
| InChi Code |
InChI=1S/C5H11NS2.Ag/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1
|
| Chemical Name |
silver;N,N-diethylcarbamodithioate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage. (2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.9041 mL | 19.5206 mL | 39.0411 mL | |
| 5 mM | 0.7808 mL | 3.9041 mL | 7.8082 mL | |
| 10 mM | 0.3904 mL | 1.9521 mL | 3.9041 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
