| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
|
||
| Other Sizes |
| Targets |
Glycidyl palmitate does not have a defined biological target as a therapeutic agent. It is a chemical intermediate used in the synthesis of various compounds. The compound may be metabolized to glycidol, which is a known genotoxic impurity, and palmitic acid. Its biological effects, if any, would be related to its metabolism and the activities of its metabolites. It is not intended for pharmacological use.
|
|---|---|
| ln Vitro |
Specific in vitro activity data for Glycidyl palmitate as a pharmacological agent are not documented in the literature. It is a chemical intermediate used in research. The compound may be used in studies of lipid metabolism or as a precursor for the synthesis of bioactive lipids such as lysophosphatidic acid. However, it is not characterized for direct biological activities such as enzyme inhibition or receptor modulation.
|
| ln Vivo |
Glycidyl palmitate is not used for in vivo pharmacological activity assessment as a drug compound. It is a chemical intermediate and a research chemical. The compound is not intended to be administered to animals for pharmacological studies. Its use in research is primarily as a synthetic intermediate or as a reference standard for the analysis of glycidyl esters in foods.
|
| Enzyme Assay |
Glycidyl palmitate is not typically used in enzyme/receptor binding assays as a test compound. Its primary applications are as a chemical intermediate and as a reference standard in analytical chemistry. When used in research, it may be employed in studies of lipid metabolism or as a standard for the quantification of glycidyl esters in food samples.
|
| Cell Assay |
Glycidyl palmitate is not used in cell-based assays as a test compound. Its primary application is as a chemical intermediate. The compound may be used in studies of lipid metabolism or as a precursor for the synthesis of bioactive lipids, but it is not characterized as a pharmacological agent for direct cellular effects. Its potential genotoxicity is a concern in food safety research.
|
| Animal Protocol |
Glycidyl palmitate is not used in animal studies as a pharmacological agent. Its primary applications are as a chemical intermediate and as a reference standard in analytical chemistry. The compound may be used in toxicological studies to assess its safety as a food contaminant, but it is not administered as a test compound for efficacy evaluations.
|
| ADME/Pharmacokinetics |
Glycidyl palmitate has a molecular weight of 312.49 g/mol and a molecular formula of C₁₉H₃₆O₃. It is a synthetic fatty acid ester found in palm and corn oils. The compound is used in the production of biodegradable polymers and in the preparation of lysophosphatidic acid. It is typically stored under standard laboratory conditions.
|
| Toxicity/Toxicokinetics |
Glycidyl palmitate is a glycidyl ester that may hydrolyze to release glycidol, a known genotoxic and carcinogenic compound. As a research chemical, standard safety precautions should be observed when handling this compound, including the use of appropriate personal protective equipment. The compound should be handled in well-ventilated areas with proper waste disposal procedures. It is not approved for human use.
|
| Additional Infomation |
Glycidyl palmitate (Oxiran-2-ylmethyl palmitate) (CAS#: 7501-44-2) has a molecular formula of C₁₉H₃₆O₃ and a molecular weight of 312.49 g/mol. It is a glycidyl fatty acid ester found in palm and corn oils. The compound is used in the production of biodegradable polymers and in the preparation of lysophosphatidic acid. This compound is not a drug and is a chemical intermediate.
|
| Molecular Formula |
C19H36O3
|
|---|---|
| Molecular Weight |
312.49
|
| Exact Mass |
312.266
|
| CAS # |
7501-44-2
|
| Related CAS # |
Glycidyl Palmitate-d5;1794941-80-2
|
| PubChem CID |
347736
|
| Appearance |
White to off-white solid powder
|
| Density |
0.938g/cm3
|
| Boiling Point |
396.3ºC at 760 mmHg
|
| Melting Point |
41-42°C (lit.)
|
| Flash Point |
152.4ºC
|
| Index of Refraction |
1.461
|
| LogP |
5.409
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
17
|
| Heavy Atom Count |
22
|
| Complexity |
265
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CCCCCCCCCCCCCCCC(=O)OCC1CO1
|
| InChi Key |
KYVUJPJYTYQNGJ-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C19H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(20)22-17-18-16-21-18/h18H,2-17H2,1H3
|
| Chemical Name |
oxiran-2-ylmethyl hexadecanoate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.2001 mL | 16.0005 mL | 32.0010 mL | |
| 5 mM | 0.6400 mL | 3.2001 mL | 6.4002 mL | |
| 10 mM | 0.3200 mL | 1.6001 mL | 3.2001 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
