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| Other Sizes |
| Targets |
N-Benzyl-N,N-dimethylbenzenaminium chloride does not have a defined biological target as a therapeutic agent. It is a quaternary ammonium salt used as a phase-transfer catalyst and as an antimicrobial agent. The compound may exert antimicrobial effects by disrupting bacterial cell membranes. However, it is not intended for systemic pharmacological use.
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| ln Vitro |
A biochemical reagent called N-Benzyl-N,N-dimethylbenzenaminium chloride can be utilized in life science research as an organic substance or biological material.
In vitro, N-Benzyl-N,N-dimethylbenzenaminium chloride exhibits antimicrobial activity against a range of bacteria and fungi. Its activity is assessed using minimum inhibitory concentration (MIC) assays against various microbial strains. The compound's antimicrobial mechanism involves disruption of cell membranes. It is not characterized for direct biological activities such as enzyme inhibition or receptor modulation on mammalian cells. |
| ln Vivo |
N-Benzyl-N,N-dimethylbenzenaminium chloride is not used for in vivo pharmacological activity assessment as a therapeutic agent. It may be used as an antiseptic or disinfectant in topical formulations. The compound is not intended to be administered systemically for pharmacological studies. Its safety has been evaluated in the context of its use as a disinfectant.
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| Enzyme Assay |
In vitro antimicrobial assays for N-Benzyl-N,N-dimethylbenzenaminium chloride typically involve determining its minimum inhibitory concentration (MIC) against various microbial strains using broth dilution or agar diffusion methods. The compound is tested against bacteria and fungi to assess its broad-spectrum antimicrobial activity. Standard microbiological protocols are employed for these assays.
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| Cell Assay |
N-Benzyl-N,N-dimethylbenzenaminium chloride is not used in cell-based assays as a test compound for pharmacological effects. Its primary applications are as a phase-transfer catalyst and as an antimicrobial agent. The compound may be used in studies of antimicrobial activity or as a control compound. It is not characterized for direct cellular effects on mammalian cells.
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| Animal Protocol |
N-Benzyl-N,N-dimethylbenzenaminium chloride is not used in animal studies as a pharmacological agent. It may be used as a disinfectant or antiseptic in topical applications. The compound's safety has been evaluated in toxicological studies. It is not administered as a test compound for efficacy evaluations.
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| ADME/Pharmacokinetics |
N-Benzyl-N,N-dimethylbenzenaminium chloride has a molecular weight of 247.76 g/mol and a molecular formula of C₁₅H₁₈ClN. It is a white to off-white crystalline solid. The compound is used as a phase-transfer catalyst and as an antimicrobial agent. It is typically stored under standard laboratory conditions.
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| Toxicity/Toxicokinetics |
N-Benzyl-N,N-dimethylbenzenaminium chloride is intended for research and industrial use only and is not approved for human therapeutic applications. As an antimicrobial agent, it may cause skin and eye irritation. Standard safety precautions should be observed when handling this compound, including the use of appropriate personal protective equipment. The compound should be handled in well-ventilated areas with proper waste disposal procedures.
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| Additional Infomation |
N-Benzyl-N,N-dimethylbenzenaminium chloride (Phenylbenzyldimethylammonium chloride) (CAS#: 3204-68-0) has a molecular formula of C₁₅H₁₈ClN and a molecular weight of 247.76 g/mol. It is a quaternary ammonium salt used as a phase-transfer catalyst and as an antimicrobial agent. This compound is not a drug and is a chemical reagent.
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| Molecular Formula |
C15H18CLN
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|---|---|
| Molecular Weight |
247.76
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| Exact Mass |
247.112
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| CAS # |
3204-68-0
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| PubChem CID |
76668
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| Appearance |
Light green to green solid powder
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| Melting Point |
134-138ºC
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| LogP |
0.457
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
3
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| Heavy Atom Count |
17
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| Complexity |
198
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C[N+](C)(CC1=CC=CC=C1)C2=CC=CC=C2.[Cl-]
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| InChi Key |
QLRKASHXFNIPLZ-UHFFFAOYSA-M
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| InChi Code |
InChI=1S/C15H18N.ClH/c1-16(2,15-11-7-4-8-12-15)13-14-9-5-3-6-10-14;/h3-12H,13H2,1-2H3;1H/q+1;/p-1
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| Chemical Name |
benzyl-dimethyl-phenylazanium;chloride
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.0362 mL | 20.1808 mL | 40.3616 mL | |
| 5 mM | 0.8072 mL | 4.0362 mL | 8.0723 mL | |
| 10 mM | 0.4036 mL | 2.0181 mL | 4.0362 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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