![[C3MPr]NTf2](/upload/1124/V66434.png)
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| Other Sizes |
| Targets |
There is no biological target for this compound. It is an ionic liquid that may interact with cell membranes if accidentally released, but it has no specific molecular target. Its primary function is as a solvent or electrolyte in materials science.
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| ln Vitro |
No in vitro biological activity is reported. In electrochemical assays, [C3MPr]NTf2 exhibits high ionic conductivity (2-10 mS/cm at 25degC), wide electrochemical window (up to 5.5 V vs. Li+/Li), and high thermal stability (decomposition >300degC). It is used as a non-aqueous electrolyte.
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| ln Vivo |
No in vivo activity is reported. This compound is not used in animals. It is a chemical reagent for non-biological applications.
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| Enzyme Assay |
Not applicable. A standard electrochemical protocol: [C3MPr]NTf2 is mixed with a lithium salt (e.g., LiTFSI) to 1 M concentration. The solution is degassed and used as an electrolyte in a two-electrode or three-electrode cell with metallic lithium or graphite electrodes. Cyclic voltammetry is performed at scan rates of 0.1-10 mV/s.
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| Cell Assay |
No cell-based protocol exists. Ionic liquids can be cytotoxic due to membrane disruption. For cytotoxicity testing, cells (e.g., HeLa or PC12) are exposed to [C3MPr]NTf2 at concentrations of 0.1-10 mM for 24-72 hours, and viability is measured by MTT. However, this is not standard use.
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| Animal Protocol |
No standard in vivo protocol. If accidental exposure occurs in animals, toxicity studies would be performed, but it is not intentionally administered.
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| ADME/Pharmacokinetics |
PK properties are not applicable. The ionic liquid has negligible volatility and is not absorbed systemically under normal handling. It is miscible with some organic solvents but immiscible with water. Formulation is as neat liquid or in organic solvents.
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| Toxicity/Toxicokinetics |
Toxicity: Ionic liquids can be toxic to aquatic organisms. [C3MPr]NTf2 may be irritating to skin and eyes, and aspiration into lungs is harmful. It is not considered highly toxic orally (LD50 >2000 mg/kg in rats for similar ionic liquids). Handle with PPE (gloves, goggles) in a well-ventilated area.
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| References | |
| Additional Infomation |
[C3MPr]NTf2 is a room-temperature ionic liquid used in energy storage devices (supercapacitors, lithium-ion batteries), electrodeposition, and as a green solvent for organic synthesis. Its high electrochemical stability makes it suitable for high-voltage applications. This product is for research use only.
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| Molecular Formula |
C10H18F6N2O4S2
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|---|---|
| Molecular Weight |
408.38
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| Exact Mass |
408.061
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| CAS # |
223437-05-6
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| PubChem CID |
25171607
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| Appearance |
Colorless to light yellow liquid（Density：1.44 g/cm3）
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| Melting Point |
12 °C
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| Index of Refraction |
1.42
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| LogP |
4.816
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
11
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| Rotatable Bond Count |
4
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| Heavy Atom Count |
24
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| Complexity |
456
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CCC[N+]1(C)CCCC1.C(F)(F)(F)S(=O)(=O)[N-]S(=O)(=O)C(F)(F)F
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| InChi Key |
DKNRELLLVOYIIB-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C8H18N.C2F6NO4S2/c1-3-6-9(2)7-4-5-8-9;3-1(4,5)14(10,11)9-15(12,13)2(6,7)8/h3-8H2,1-2H3;/q+1;-1
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| Chemical Name |
bis(trifluoromethylsulfonyl)azanide;1-methyl-1-propylpyrrolidin-1-ium
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ~200 mg/mL (~489.7 mM; with ultrasonication)
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| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 5 mg/mL (12.24 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 5 mg/mL (12.24 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of 20% SBE-β-CD saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 5 mg/mL (12.24 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of corn oil and mix well. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.4487 mL | 12.2435 mL | 24.4870 mL | |
| 5 mM | 0.4897 mL | 2.4487 mL | 4.8974 mL | |
| 10 mM | 0.2449 mL | 1.2243 mL | 2.4487 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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