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| Other Sizes |
| Targets |
Carboxyl methylstarch sodium does not have a defined biological target as a therapeutic agent. It is a modified starch derivative used as a thickening agent, stabilizer, and binder in various formulations. The compound is not intended to exert pharmacological effects. Its utility lies in its physical and chemical properties as a water-soluble polysaccharide.
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| ln Vitro |
Specific in vitro activity data for Carboxyl methylstarch sodium as a pharmacological agent are not documented in the literature, as it is primarily used as an excipient and thickening agent. The compound is not characterized for direct biological activities such as enzyme inhibition, receptor modulation, or antimicrobial effects. Its effects in biological systems are primarily related to its physical properties.
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| ln Vivo |
Carboxyl methylstarch sodium is not used for in vivo pharmacological activity assessment as a drug compound. It is an excipient and thickening agent used in food, pharmaceutical, and cosmetic formulations. The compound is not intended to be administered for therapeutic purposes. Its safety has been evaluated in the context of its use as a food additive and pharmaceutical excipient.
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| Enzyme Assay |
Carboxyl methylstarch sodium is not typically used in enzyme/receptor binding assays as a test compound. Its primary applications are as a thickening agent and stabilizer. When used in research, it may be employed in studies of polysaccharide properties or as a component of formulations. Standard chemical and physical protocols are employed for its characterization.
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| Cell Assay |
Carboxyl methylstarch sodium is not used in cell-based assays as a test compound for pharmacological effects. Its primary applications are as an excipient and thickening agent. The compound may be used in studies of cell interactions with polysaccharides, but it is not characterized as a pharmacological agent for direct cellular effects.
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| Animal Protocol |
Carboxyl methylstarch sodium is not used in animal studies as a pharmacological agent. Its primary applications are as an excipient and thickening agent in food, pharmaceutical, and cosmetic formulations. The compound may be used in safety studies to assess its irritation and sensitization potential. It is not administered as a test compound for efficacy evaluations.
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| ADME/Pharmacokinetics |
Carboxyl methylstarch sodium is a modified starch derivative with a variable molecular weight. It is a white to off-white powder. The compound is a sodium salt of carboxymethyl starch, used as a thickening agent, stabilizer, binder, and tablet disintegrant. It is typically stored under standard laboratory conditions, protected from moisture.
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| Toxicity/Toxicokinetics |
Carboxyl methylstarch sodium is intended for research and industrial use only and is not approved for human therapeutic applications. As a food additive and pharmaceutical excipient, it has been evaluated for safety in various applications. Standard safety precautions should be observed when handling this compound, including the use of appropriate personal protective equipment.
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| Additional Infomation |
Carboxyl methylstarch sodium (CAS#: 9063-38-1) is a modified starch derivative used as a thickening agent, stabilizer, binder, and tablet disintegrant in food, pharmaceutical, and cosmetic formulations. This compound is not a drug and is an excipient.
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| Molecular Formula |
C8H15N3O
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|---|---|
| Molecular Weight |
169.2242
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| Exact Mass |
290.097
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| CAS # |
9063-38-1
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| PubChem CID |
47207535
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| Appearance |
White to off-white solid powder
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
5
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| Heavy Atom Count |
17
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| Complexity |
342
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CCCS(=O)(=O)CC(=O)NC1=CC=C(C=C1)F
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| InChi Key |
COTYJDILSJMZTQ-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C11H14FNO3S/c1-2-7-17(15,16)8-11(14)13-10-5-3-9(12)4-6-10/h3-6H,2,7-8H2,1H3,(H,13,14)
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| Chemical Name |
N-(4-fluorophenyl)-2-propylsulfonylacetamide
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.9095 mL | 29.5473 mL | 59.0947 mL | |
| 5 mM | 1.1819 mL | 5.9095 mL | 11.8189 mL | |
| 10 mM | 0.5909 mL | 2.9547 mL | 5.9095 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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