| Size | Price | Stock | Qty |
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| 5mg |
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| 10mg |
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| Other Sizes |
| Targets |
15-Methylpalmitic acid does not have a defined pharmacological target as it is a biochemical reagent and fatty acid. The compound has been extensively studied for its unique structural properties and its role in lipid metabolism and membrane biology. In metabolic studies, it serves as a key molecule for investigating the activity and specificity of enzymes involved in the biosynthesis and degradation of branched-chain fatty acids. It may be involved in the regulation of fat metabolism.
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| ln Vitro |
In vitro activity of 15-Methylpalmitic acid is assessed in lipid metabolism studies. The compound is used to investigate how branched-chain fatty acids influence the structure and function of lipid rafts, cellular signaling platforms, and the integration of transmembrane proteins. Its branched chain disrupts regular lipid packing, thereby modulating membrane fluidity and permeability.
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| ln Vivo |
No specific in vivo pharmacological activity data have been documented for 15-Methylpalmitic acid as a therapeutic agent. The compound is used in lipid research, particularly in the study of branched-chain fatty acids (BCFAs), which are essential for maintaining cellular membrane integrity and fluidity, especially in bacteria. It is not administered to animals for pharmacological evaluation.
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| Enzyme Assay |
For non-cellular assays, 15-Methylpalmitic acid is characterized by standard analytical techniques including GC, HPLC, NMR, and mass spectrometry to confirm identity and purity. The compound can be evaluated in lipid metabolism studies and membrane dynamics research. Typical protocols involve dissolving the compound in appropriate solvents and analyzing by chromatographic methods. Purity is typically ≥95% to ≥98%. Molecular weight: 270.45.
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| Cell Assay |
For in vitro cell-based studies, 15-Methylpalmitic acid can be used in cell culture to study lipid metabolism and membrane dynamics. Cells are cultured under standard conditions and treated with the compound to assess effects on membrane fluidity, lipid raft formation, and cellular signaling. The compound is typically dissolved in organic solvents such as ethanol or DMSO and diluted in cell culture medium. Appropriate controls should be included.
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| Animal Protocol |
For in vivo animal studies, 15-Methylpalmitic acid can be formulated using standard injection vehicles. The compound is a solid at room temperature. Dosing solutions should be freshly prepared and administered according to specific protocols with appropriate control groups. Standard handling procedures for fatty acids should be followed.
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| ADME/Pharmacokinetics |
15-Methylpalmitic acid has a molecular weight of 270.45 and molecular formula C17H34O2. Purity: typically ≥95% to ≥98%. Storage: keep in a cool, dry place protected from light and moisture. The compound is a solid at room temperature. Solubility: soluble in organic solvents. The compound is stable under recommended storage conditions.
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| Toxicity/Toxicokinetics |
15-Methylpalmitic acid is for research use only and not for human consumption. Standard laboratory safety practices should be followed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses should be worn. Specific LD50 values and detailed toxicological profiles have not been extensively reported.
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| Additional Infomation |
Isohexadecanoic acid is a branched-chain saturated fatty acid formed by replacing the methyl group at the 15-position of hexadecanoic acid (palmitic acid). It is a branched-chain saturated fatty acid, a long-chain fatty acid, and a methyl-branched fatty acid. It is the conjugate acid of isohexadecanoic acid. 15-Methylhexadecanoic acid has been reported in potatoes, fruit flies, and other organisms with relevant data.
15-Methylpalmitic acid (CAS 1603-03-8) is also known as 15-methylhexadecanoic acid. It is a methylated fatty acid widely found in animal lipids that may be involved in the regulation of fat metabolism. Research applications include the study of lipid membrane dynamics, branched-chain fatty acid metabolism, and the structure and function of lipid rafts. No clinical trials or therapeutic approvals exist. |
| Molecular Formula |
C17H34O2
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|---|---|
| Molecular Weight |
270.45
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| Exact Mass |
270.256
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| CAS # |
1603-03-8
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| PubChem CID |
164860
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| Appearance |
Typically exists as solid at room temperature
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| Density |
0.889g/cm3
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| Boiling Point |
386.1ºC at 760mmHg
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| Flash Point |
216.6ºC
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| Vapour Pressure |
4.94E-07mmHg at 25°C
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| Index of Refraction |
1.453
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| LogP |
5.798
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
14
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| Heavy Atom Count |
19
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| Complexity |
199
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| Defined Atom Stereocenter Count |
0
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| SMILES |
OC(CCCCCCCCCCCCCC(C)C)=O
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| InChi Key |
IIUXHTGBZYEGHI-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C17H34O2/c1-16(2)14-12-10-8-6-4-3-5-7-9-11-13-15-17(18)19/h16H,3-15H2,1-2H3,(H,18,19)
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| Chemical Name |
15-methylhexadecanoic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.6975 mL | 18.4877 mL | 36.9754 mL | |
| 5 mM | 0.7395 mL | 3.6975 mL | 7.3951 mL | |
| 10 mM | 0.3698 mL | 1.8488 mL | 3.6975 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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