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| Other Sizes |
| Targets |
8-Nonen-1-ol does not have a defined pharmacological target as it is a chemical reagent and natural product. The compound exhibits notable antimicrobial activity and has been shown to possess antiulcer and healing activities, which are attributed to its antioxidant and cytoprotective mechanisms. It is used as a flavoring agent and fragrance in various products and as a reactant in the synthesis of chlorosulfolipid (+)-danicalipin A.
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| ln Vitro |
In vitro studies have demonstrated that 8-Nonen-1-ol exhibits notable antimicrobial activity. The compound has been shown to possess antiulcer and healing activities, attributed to its antioxidant and cytoprotective mechanisms. It has also been reported to have cytotoxicity towards various mammalian cells. In research settings, the compound is used as a biochemical reagent for life science research.
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| ln Vivo |
No specific in vivo pharmacological activity data have been documented for 8-Nonen-1-ol as a therapeutic agent. The compound is used primarily as a flavoring agent, fragrance, and chemical intermediate. If used in animal studies, it would be administered for specific research purposes such as studying antimicrobial or antiulcer activities. The compound is not developed as a therapeutic agent.
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| Enzyme Assay |
For non-cellular assays, 8-Nonen-1-ol is characterized by standard analytical techniques including GC, NMR, and mass spectrometry to confirm identity and purity. The compound can be evaluated as a substrate in various organic reactions including oxidation, reduction, and dehydration reactions. Typical protocols involve dissolving the compound in appropriate solvents and analyzing reaction products by chromatographic methods. Purity is typically ≥95% to ≥98%. Molecular weight: 142.24.
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| Cell Assay |
For in vitro cell-based studies, 8-Nonen-1-ol can be used to assess antimicrobial activity and cytotoxicity. Cells are cultured under standard conditions and treated with the compound at various concentrations to evaluate effects on cell viability and microbial growth. The compound has been reported to have cytotoxicity towards various mammalian cells. Appropriate controls should be included in the experimental design.
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| Animal Protocol |
For in vivo animal studies, 8-Nonen-1-ol can be formulated using standard injection vehicles. The compound is a liquid at room temperature. Dosing solutions should be freshly prepared and administered according to specific protocols with appropriate control groups. Standard handling procedures for alcohols and alkenes should be followed.
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| ADME/Pharmacokinetics |
8-Nonen-1-ol has a molecular weight of 142.24 and molecular formula C9H18O. Purity: typically ≥95% to ≥98%. Storage: keep in a cool, dry place protected from light and moisture. The compound is a liquid at room temperature. Solubility: soluble in common organic solvents. The compound is stable under recommended storage conditions.
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| Toxicity/Toxicokinetics |
8-Nonen-1-ol is for research use only and not for human consumption. Standard laboratory safety practices should be followed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses should be worn. Specific LD50 values and detailed toxicological profiles have not been extensively reported. The compound should be handled with care as with all laboratory chemicals.
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| Additional Infomation |
8-Nonen-1-ol (CAS 13038-21-6) is also known as 8-nonen-1-ol. It is used as a flavoring agent and fragrance in various products, as a solvent and intermediate in organic synthesis, and as a reactant in the synthesis of chlorosulfolipid (+)-danicalipin A. The compound has antimicrobial activity and antiulcer and healing activities attributed to antioxidant and cytoprotective mechanisms. No clinical trials or therapeutic approvals exist.
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| Molecular Formula |
C9H18O
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|---|---|
| Molecular Weight |
142.24
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| Exact Mass |
142.135
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| CAS # |
13038-21-6
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| PubChem CID |
11094728
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| Appearance |
Colorless to light yellow liquid（Density：0.85 g/cm3）
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| Density |
0.8±0.1 g/cm3
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| Boiling Point |
197.9±9.0 °C at 760 mmHg
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| Flash Point |
79.0±10.4 °C
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| Vapour Pressure |
0.1±0.8 mmHg at 25°C
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| Index of Refraction |
1.443
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| LogP |
3.02
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
7
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| Heavy Atom Count |
10
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| Complexity |
69.1
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C=CCCCCCCCO
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| InChi Key |
FKGFCVJJLGSFSB-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C9H18O/c1-2-3-4-5-6-7-8-9-10/h2,10H,1,3-9H2
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| Chemical Name |
non-8-en-1-ol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.0304 mL | 35.1519 mL | 70.3037 mL | |
| 5 mM | 1.4061 mL | 7.0304 mL | 14.0607 mL | |
| 10 mM | 0.7030 mL | 3.5152 mL | 7.0304 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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