| Size | Price | Stock | Qty |
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| 100mg |
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| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
Lignoceryl alcohol does not have a defined pharmacological target as it is a long-chain fatty alcohol and biochemical reagent. The compound is used as a thickening agent, stabilizer, emulsifier, and surfactant. As a fatty alcohol, it has antibacterial properties and has been shown in vitro to effectively inhibit bacterial growth. It is used in skin creams and lotions for its emollient properties, providing smooth texture and enhancing moisture retention.
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| ln Vitro |
In vitro activity of Lignoceryl alcohol has been studied for its antibacterial properties, demonstrating effective inhibition of bacterial growth. In research settings, the compound is used as a biochemical reagent for life science research. It serves as a reference standard in lipid metabolism research and is utilized in biochemical studies investigating membrane composition and lipid signaling pathways.
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| ln Vivo |
No specific in vivo pharmacological activity data have been documented for Lignoceryl alcohol as a therapeutic agent. The compound is used primarily in cosmetic formulations and as a biochemical reagent. If used in animal studies, it would be administered for lipid metabolism research or membrane studies. The compound is not developed as a therapeutic agent and is not administered for pharmacological evaluation.
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| Enzyme Assay |
For non-cellular assays, Lignoceryl alcohol is characterized by standard analytical techniques including GC, HPLC, NMR, and mass spectrometry to confirm identity and purity. The compound can be evaluated as a standard in lipid analysis and as a substrate in various organic reactions. Typical protocols involve dissolving the compound in appropriate organic solvents and analyzing by chromatographic methods. Purity: ≥98%. Molecular weight: 354.65.
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| Cell Assay |
For in vitro cell-based studies, Lignoceryl alcohol is not typically used as a direct test compound. The compound is used in biochemical studies investigating membrane composition and lipid signaling pathways in in vitro models. If used in cell culture, the compound is typically dissolved in organic solvents such as ethanol or DMSO and diluted in cell culture medium. Appropriate controls should be included in the experimental design.
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| Animal Protocol |
For in vivo animal studies, Lignoceryl alcohol can be formulated using standard injection vehicles. The compound is a waxy solid at room temperature. Dosing solutions should be freshly prepared and administered according to specific protocols with appropriate control groups. Standard handling procedures for long-chain fatty alcohols should be followed. The compound is used in lipid metabolism research.
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| ADME/Pharmacokinetics |
Lignoceryl alcohol has a molecular weight of 354.65 and molecular formula C24H50O. It appears as a white, odorless, waxy solid that is insoluble in water but mixes well with organic solvents. Purity: ≥98%. Storage: keep in a cool, dry place protected from light and moisture. The compound is stable under recommended storage conditions. Solubility: soluble in organic solvents, insoluble in water.
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| Toxicity/Toxicokinetics |
Lignoceryl alcohol is for research use only and not for human consumption. Standard laboratory safety practices should be followed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses should be worn. Specific LD50 values and detailed toxicological profiles have not been extensively reported. The compound should be handled with care as with all laboratory chemicals.
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| Additional Infomation |
Tetracosyl-1-ol is a long-chain primary fatty alcohol formed by replacing the hydrogen atom at the terminal carbon atom of a tetracosane molecule with a hydroxyl group. It has been isolated from various plants, including grape seeds, evening primrose (Oenothera biennis), dragon fruit (Hylocereus polyrhizus and Hylocereus undatus), and jasmine (Jasminum sambac). It is a plant metabolite and wound-healing agent. It is a long-chain primary fatty alcohol belonging to the tetracosyl alcohol family. Tetracosyl alcohol has been reported to exist in Castanopsis lanceifolia, Artemisia igniaria, and several other organisms with relevant data. See also: Saw Palmetto (partial).
Lignoceryl alcohol (CAS 506-51-4) is also known as 1-tetracosanol and tetracosyl alcohol. It naturally occurs in lanolin and green leaf composite samples. Applications include cosmetic formulations as an emollient, as a thickening agent, stabilizer, emulsifier, and surfactant, as a reference standard in lipid metabolism research, and as an intermediate in organic synthesis. No clinical trials or therapeutic approvals exist. |
| Molecular Formula |
C24H50O
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|---|---|
| Molecular Weight |
354.65
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| Exact Mass |
354.386
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| CAS # |
506-51-4
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| PubChem CID |
10472
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| Appearance |
Typically exists as solid at room temperature
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| Density |
0.8±0.1 g/cm3
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| Boiling Point |
394.5±5.0 °C at 760 mmHg
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| Melting Point |
77 °C
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| Flash Point |
141.7±5.2 °C
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| Vapour Pressure |
0.0±2.1 mmHg at 25°C
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| Index of Refraction |
1.456
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| LogP |
11.5
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
22
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| Heavy Atom Count |
25
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| Complexity |
214
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| Defined Atom Stereocenter Count |
0
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| SMILES |
O([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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| InChi Key |
TYWMIZZBOVGFOV-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C24H50O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25/h25H,2-24H2,1H3
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| Chemical Name |
tetracosan-1-ol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.8197 mL | 14.0984 mL | 28.1968 mL | |
| 5 mM | 0.5639 mL | 2.8197 mL | 5.6394 mL | |
| 10 mM | 0.2820 mL | 1.4098 mL | 2.8197 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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