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| Other Sizes |
| Targets |
Tetraethylammonium tetrafluoroborate does not have a defined pharmacological target as it is a chemical reagent and electrolyte. The compound is used as a supporting electrolyte in electrochemical applications and as a phase transfer catalyst in organic synthesis. It finds application as an electrolyte additive in the capillary electrophoretic separation of polyphenols found in grape seed extracts. Its primary function is to facilitate chemical and electrochemical reactions.
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| ln Vitro |
Tetraethylammonium tetrafluoroborate is a biochemical reagent that can be utilized in research pertaining to life sciences as an organic compound or biological material.
No specific in vitro pharmacological activity data are available for Tetraethylammonium tetrafluoroborate as it is a chemical reagent. In research settings, the compound is used as a phase transfer catalyst, electrolyte, and electrolyte additive. Its activity is assessed in terms of catalytic efficiency, ionic conductivity, and electrochemical performance rather than direct biological activity. |
| ln Vivo |
No specific in vivo pharmacological activity data have been documented for Tetraethylammonium tetrafluoroborate as a therapeutic agent. The compound is used exclusively as a chemical reagent and electrolyte. It is not administered to animals for pharmacological evaluation. Its applications are limited to organic synthesis, electrochemistry, and analytical chemistry laboratories.
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| Enzyme Assay |
For non-cellular assays, Tetraethylammonium tetrafluoroborate is characterized by standard analytical techniques including NMR, HPLC, and elemental analysis to confirm identity and purity. Purity is typically ≥95-99%. The compound has a melting point of approximately 300°C and is soluble in water. Typical protocols involve using the compound as a supporting electrolyte in electrochemical cells or as a phase transfer catalyst in organic reactions. Storage: room temperature in a cool and dry place.
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| Cell Assay |
For in vitro cell-based studies, Tetraethylammonium tetrafluoroborate is not typically used as a direct test compound. It is a chemical reagent for synthetic chemistry and electrochemical applications. If handled in a biological laboratory context, appropriate safety precautions should be taken due to the quaternary ammonium structure and potential irritant properties. The compound is a solid at room temperature.
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| Animal Protocol |
For in vivo animal studies, Tetraethylammonium tetrafluoroborate is not typically administered as a test compound. It is used as a chemical reagent and electrolyte. If used in toxicological studies, it would be administered via appropriate routes with suitable formulations. The toxicological properties of this substance have not been fully investigated. Causes respiratory tract irritation and skin irritation.
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| ADME/Pharmacokinetics |
Tetraethylammonium tetrafluoroborate has a molecular weight of 217.06 and formula C₈H₂₀BF₄N. It appears as a white solid with a melting point of approximately 300°C. Solubility: soluble in water. Storage: room temperature in a cool and dry place. Purity: typically ≥95-99%. The compound is a quaternary ammonium salt.
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| Toxicity/Toxicokinetics |
Tetraethylammonium tetrafluoroborate is for research use only and not for human consumption. Standard laboratory safety practices should be followed when handling this chemical. The compound is a skin and respiratory tract irritant. Appropriate personal protective equipment including gloves and safety glasses should be worn. The toxicological properties have not been fully investigated.
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| Additional Infomation |
Tetraethylammonium tetrafluoroborate (CAS 429-06-1) is also known as tetraethylazanium tetrafluoroborate. It is a quaternary ammonium salt used as a supporting electrolyte in electrochemical applications, as a phase transfer catalyst in organic synthesis, and as an electrolyte additive in capillary electrophoretic separation. No clinical trials or therapeutic approvals exist.
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| Molecular Formula |
C8H20BF4N
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|---|---|
| Molecular Weight |
217.06
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| Exact Mass |
217.162
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| CAS # |
429-06-1
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| PubChem CID |
2724277
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| Appearance |
White to off-white solid powder
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| Melting Point |
≥300 °C(lit.)
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| LogP |
3.182
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
5
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| Rotatable Bond Count |
4
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| Heavy Atom Count |
14
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| Complexity |
66.6
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| Defined Atom Stereocenter Count |
0
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| SMILES |
F[B-](F)(F)F.[N+](C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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| InChi Key |
XJRAKUDXACGCHA-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C8H20N.BF4/c1-5-9(6-2,7-3)8-4;2-1(3,4)5/h5-8H2,1-4H3;/q+1;-1
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| Chemical Name |
tetraethylazanium;tetrafluoroborate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.6070 mL | 23.0351 mL | 46.0702 mL | |
| 5 mM | 0.9214 mL | 4.6070 mL | 9.2140 mL | |
| 10 mM | 0.4607 mL | 2.3035 mL | 4.6070 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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