| Size | Price | Stock | Qty |
|---|---|---|---|
| 1mg |
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| 5mg |
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| Other Sizes |
| Targets |
Not applicable (fatty acid). trans-10-Heptadecenoic acid is a monounsaturated fatty acid used as a research tool for studying fatty acid metabolism and the biological effects of trans fatty acids.
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|---|---|
| ln Vitro |
trans-10-Heptadecenoic acid is a monounsaturated fatty acid used in research on fatty acid metabolism. Its in vitro effects include incorporation into cell membranes and modulation of lipid metabolism. The compound is used to study the biological effects of trans fatty acids.
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| ln Vivo |
In vivo studies of trans-10-heptadecenoic acid are conducted in animal models to assess its effects on fatty acid metabolism, inflammation, and other physiological processes. The compound is administered orally or via dietary supplementation.
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| Enzyme Assay |
Non-cell-based assays for trans-10-heptadecenoic acid include its use as a standard in fatty acid analysis by GC or GC-MS. Standard analytical methods are used for compound characterization and purity assessment.
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| Cell Assay |
Cell-based assays for trans-10-heptadecenoic acid use various cell lines to study fatty acid uptake, metabolism, and effects on cellular functions. The compound's effects on lipid metabolism, inflammation, and cell signaling can be assessed.
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| Animal Protocol |
In vivo studies of trans-10-heptadecenoic acid are conducted in animal models to study fatty acid metabolism and the effects of trans fatty acids. The compound is administered orally or via dietary supplementation. Metabolic parameters, inflammatory markers, and tissue fatty acid composition are assessed.
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| ADME/Pharmacokinetics |
trans-10-Heptadecenoic acid has a molecular formula of C₁₇H₃₂O₂ and a molecular weight of approximately 268.43 g/mol. It is a monounsaturated fatty acid with a trans double bond at the 10-position. The compound is soluble in organic solvents. It should be stored under recommended conditions.
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| Toxicity/Toxicokinetics |
Specific toxicity data for trans-10-heptadecenoic acid are limited. As a fatty acid, it is generally considered to have low toxicity. Standard laboratory safety practices should be followed when handling this compound.
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| References | |
| Additional Infomation |
10-heptadecenoic acid is a heptadecenoic acid with the double bond located at position 10. It is the conjugate acid of 10-heptadecenoic acid ester. Trans-10-heptadecenoic acid has been reported in Monascus purpureus, and relevant data are available for reference.
trans-10-Heptadecenoic acid is a monounsaturated fatty acid with a trans double bond at the 10-position. It is used as a research tool for studying fatty acid metabolism and the biological effects of trans fatty acids. It is for research use only. |
| Molecular Formula |
C17H32O2
|
|---|---|
| Molecular Weight |
268.43
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| Exact Mass |
268.24
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| CAS # |
126761-43-1
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| Related CAS # |
cis-10-Heptadecenoic acid;29743-97-3
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| PubChem CID |
5312434
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| Appearance |
Colorless to light yellow liquid
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| Density |
0.9±0.1 g/cm3
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| Boiling Point |
354.0±11.0 °C at 760 mmHg
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| Flash Point |
250.9±14.4 °C
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| Vapour Pressure |
0.0±1.7 mmHg at 25°C
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| Index of Refraction |
1.466
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| LogP |
7.17
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
14
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| Heavy Atom Count |
19
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| Complexity |
221
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CCCCCC/C=C/CCCCCCCCC(O)=O
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| InChi Key |
GDTXICBNEOEPAZ-BQYQJAHWSA-N
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| InChi Code |
InChI=1S/C17H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19/h7-8H,2-6,9-16H2,1H3,(H,18,19)/b8-7+
|
| Chemical Name |
(E)-heptadec-10-enoic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.7254 mL | 18.6268 mL | 37.2537 mL | |
| 5 mM | 0.7451 mL | 3.7254 mL | 7.4507 mL | |
| 10 mM | 0.3725 mL | 1.8627 mL | 3.7254 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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