| Size | Price | Stock | Qty |
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| 50mg |
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| 100mg |
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| Other Sizes |
| Targets |
4,5-Dimethoxybenzene-1,2-diamine does not have biological targets. It is a chemical reagent used for analytical detection of aldehydes and biomarkers. The compound reacts with aldehydes to form fluorescent benzimidazole derivatives, making it a useful tool for detecting these compounds in biological and environmental samples.
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| ln Vitro |
4,5-Dimethoxybenzene-1,2-diamine is not a therapeutic compound and has no biological activity. It is a chemical reagent used for analytical purposes. The compound reacts with aldehydes to produce highly fluorescent benzimidazole derivatives, allowing for sensitive detection of aldehydes in various samples. It can be used for the determination of methyldioxal (an intermediate product of glycolysis) and diabetic ketoacidosis biomarkers.
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| ln Vivo |
4,5-Dimethoxybenzene-1,2-diamine is not used in vivo as it is a chemical reagent rather than a therapeutic compound. It may be used in ex vivo analyses to detect aldehydes or biomarkers in biological samples such as blood, urine, or tissue extracts.
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| Enzyme Assay |
The aldehyde detection assay using 4,5-Dimethoxybenzene-1,2-diamine involves reacting the compound with aldehydes in solution. The reaction produces highly fluorescent benzimidazole derivatives. Fluorescence is measured at appropriate excitation and emission wavelengths, and the concentration of aldehydes is determined by comparing to a standard curve. The compound has a molecular formula of C₈H₁₂N₂O₂ and a molecular weight of 168.19 g/mol.
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| Cell Assay |
4,5-Dimethoxybenzene-1,2-diamine is not used in cellular assays as it is not a biologically active compound. It is a chemical reagent used for analytical detection. For research use, it is handled as a chemical reagent under standard laboratory conditions. The compound has a molecular formula of C₈H₁₂N₂O₂ and a molecular weight of 168.19 g/mol and a purity of ≥95%.
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| Animal Protocol |
No in vivo protocols for 4,5-Dimethoxybenzene-1,2-diamine are reported. The compound is not used in animal studies.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for 4,5-Dimethoxybenzene-1,2-diamine are not applicable as it is not a therapeutic compound. The compound has a molecular formula of C₈H₁₂N₂O₂ and a molecular weight of 168.19 g/mol.
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| Toxicity/Toxicokinetics |
4,5-Dimethoxybenzene-1,2-diamine is a chemical reagent and should be handled with appropriate safety precautions. It may cause irritation to skin, eyes, and respiratory tract. Standard laboratory safety practices should be followed, including the use of gloves, eye protection, and proper ventilation.
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| References | |
| Additional Infomation |
4,5-Dimethoxybenzene-1,2-diamine is a chemical reagent for detecting aldehydes and biomarkers such as methyldioxal and diabetic ketoacidosis markers. Molecular formula: C₈H₁₂N₂O₂, molecular weight: 168.19. No clinical applications exist. For research use only as an analytical reagent.
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| Molecular Formula |
C8H12N2O2
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|---|---|
| Molecular Weight |
168.19
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| Exact Mass |
168.089
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| CAS # |
27841-33-4
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| PubChem CID |
152939
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| Appearance |
Brown to black solid powder
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| Density |
1.2±0.1 g/cm3
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| Boiling Point |
329.0±37.0 °C at 760 mmHg
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| Flash Point |
174.8±20.2 °C
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| Vapour Pressure |
0.0±0.7 mmHg at 25°C
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| Index of Refraction |
1.592
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| LogP |
-0.46
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| Hydrogen Bond Donor Count |
2
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
12
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| Complexity |
127
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
SKIUVOVOIJBJPN-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C8H12N2O2/c1-11-7-3-5(9)6(10)4-8(7)12-2/h3-4H,9-10H2,1-2H3
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| Chemical Name |
4,5-dimethoxybenzene-1,2-diamine
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.9457 mL | 29.7283 mL | 59.4566 mL | |
| 5 mM | 1.1891 mL | 5.9457 mL | 11.8913 mL | |
| 10 mM | 0.5946 mL | 2.9728 mL | 5.9457 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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