| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
|
||
| 1g |
|
||
| 5g |
|
||
| Other Sizes |
| Targets |
2-Methoxyphenothiazine is classified as a drug derivative, indicating its structural similarity to other phenothiazine-based drugs. The phenothiazine core is a well-known pharmacophore found in various antipsychotic and antihistamine medications. However, its specific molecular target is not identified in the provided literature. It is primarily used as a biochemical reagent for research purposes.
|
|---|---|
| ln Vitro |
Specific in vitro biological activity data for 2-Methoxyphenothiazine are not reported in the provided literature. As a biochemical reagent, its use is likely in the synthesis or study of other compounds, rather than as a primary bioactive agent.
|
| ln Vivo |
Specific in vivo data for 2-Methoxyphenothiazine are not reported. It is not used as a therapeutic compound.
|
| Enzyme Assay |
2-Methoxyphenothiazine is not used in standard biochemical assays as a primary active compound. It is a biochemical reagent and may be used as a reference compound or in synthetic chemistry.
|
| Cell Assay |
2-Methoxyphenothiazine is not typically used in cellular assays as a bioactive compound. It is a biochemical reagent. For research use, it is typically stored as a powder at -20°C for up to 3 years or in solution at -80°C for up to 6 months.
|
| Animal Protocol |
In vivo studies for 2-Methoxyphenothiazine are not conducted as it is not a therapeutic compound.
|
| ADME/Pharmacokinetics |
Pharmacokinetic data for 2-Methoxyphenothiazine are not applicable as it is not a therapeutic compound. The compound has a molecular weight of 229.30 g/mol and is typically stored at -20°C.
|
| Toxicity/Toxicokinetics |
2-Methoxyphenothiazine is a chemical reagent and should be handled with appropriate safety precautions. Standard laboratory safety practices should be followed.
|
| References | |
| Additional Infomation |
2-Methoxy-10H-Phenothiazine is a type of phenothiazine compound.
2-Methoxyphenothiazine is a phenothiazine derivative used as a biochemical reagent. It has the molecular formula C13H11NOS. It is classified as a drug derivative. It has no clinical applications and is for research use only. |
| Molecular Formula |
C13H11NOS
|
|---|---|
| Molecular Weight |
229.30
|
| Exact Mass |
229.056
|
| CAS # |
1771-18-2
|
| PubChem CID |
74490
|
| Appearance |
Off-white to gray solid powder
|
| Density |
1.2±0.1 g/cm3
|
| Boiling Point |
408.1±34.0 °C at 760 mmHg
|
| Melting Point |
185-188°C
|
| Flash Point |
200.6±25.7 °C
|
| Vapour Pressure |
0.0±1.0 mmHg at 25°C
|
| Index of Refraction |
1.646
|
| LogP |
4.41
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
16
|
| Complexity |
248
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
S1C2=C([H])C([H])=C([H])C([H])=C2N([H])C2C([H])=C(C([H])=C([H])C1=2)OC([H])([H])[H]
|
| InChi Key |
DLYKFPHPBCTAKD-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C13H11NOS/c1-15-9-6-7-13-11(8-9)14-10-4-2-3-5-12(10)16-13/h2-8,14H,1H3
|
| Chemical Name |
2-methoxy-10H-phenothiazine
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.3611 mL | 21.8055 mL | 43.6110 mL | |
| 5 mM | 0.8722 mL | 4.3611 mL | 8.7222 mL | |
| 10 mM | 0.4361 mL | 2.1805 mL | 4.3611 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
