| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
The specific molecular targets of Cirsiumaldehyde are not fully characterized. As a natural product with two furan rings and aldehyde groups, it possesses interesting chemical properties such as the ability to form crosslinked networks. Its reported isolation from various plant sources suggests potential biological activities, but specific targets have not been identified.
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|---|---|
| ln Vitro |
Specific in vitro activity data for Cirsiumaldehyde are not reported in the available literature. As a natural product from various plant sources, it may exhibit biological activities, but studies on the isolated compound in cell-based assays are not detailed.
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| ln Vivo |
Specific in vivo data for Cirsiumaldehyde are not reported. As a research compound, it has not been described in animal model studies. Further studies are needed to evaluate its in vivo efficacy and pharmacological properties.
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| Enzyme Assay |
No specific biochemical assay protocols for Cirsiumaldehyde are detailed. As a natural product, standard assays for biological activity would depend on the specific research question. The compound has a molecular formula of C12H10O5 and a molecular weight of 234.20 g/mol.
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| Cell Assay |
For cellular studies, appropriate cell lines would be cultured in suitable media and treated with Cirsiumaldehyde at various concentrations. Cell viability would be assessed using MTT or similar assays. The compound is soluble in chloroform, dichloromethane, ethyl acetate, DMSO, and acetone.
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| Animal Protocol |
In vivo studies for Cirsiumaldehyde would be conducted in appropriate animal models depending on the research focus. However, specific published protocols for this compound are not available.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for Cirsiumaldehyde are not reported. The compound has a molecular formula of C12H10O5 and a molecular weight of 234.20 g/mol. It has very low water solubility (0.89 g/L at 25°C).
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| Toxicity/Toxicokinetics |
Toxicological data for Cirsiumaldehyde are not reported. As a research compound, comprehensive toxicology studies have not been published. The compound should be handled with appropriate safety precautions.
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| References | |
| Additional Infomation |
5,5'-Oxadiazine (5-methylene-2-furfural) has reportedly been found in hawthorn, citrus, and other organisms for which data is available.
Cirsiumaldehyde is a natural product from Anemone altaica with the molecular formula C12H10O5 and molecular weight 234.20 g/mol. No clinical trials exist. For research use only. |
| Molecular Formula |
C12H10O5
|
|---|---|
| Molecular Weight |
234.20
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| Exact Mass |
234.053
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| CAS # |
7389-38-0
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| PubChem CID |
12366272
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.313g/cm3 at 25 ℃
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| Boiling Point |
404.8士45.0°℃
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| Melting Point |
113.5-115.5℃
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| LogP |
2.214
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
5
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| Rotatable Bond Count |
6
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| Heavy Atom Count |
17
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| Complexity |
242
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| Defined Atom Stereocenter Count |
0
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| SMILES |
O(CC1=CC=C(C=O)O1)CC1=CC=C(C=O)O1
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| InChi Key |
TZTWOBUHCLWLNK-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C12H10O5/c13-5-9-1-3-11(16-9)7-15-8-12-4-2-10(6-14)17-12/h1-6H,7-8H2
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| Chemical Name |
5-[(5-formylfuran-2-yl)methoxymethyl]furan-2-carbaldehyde
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.2699 mL | 21.3493 mL | 42.6985 mL | |
| 5 mM | 0.8540 mL | 4.2699 mL | 8.5397 mL | |
| 10 mM | 0.4270 mL | 2.1349 mL | 4.2699 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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