| Size | Price | Stock | Qty |
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| 1mg |
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| 5mg |
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| Other Sizes |
| Targets |
The molecular targets of Vanillic acid glucoside are not fully characterized. As a hydrolyzable tannin, it may interact with proteins and enzymes through hydrogen bonding and hydrophobic interactions. The compound is a glucoside of vanillic acid, a known antioxidant, suggesting it may exert its effects through radical scavenging and modulation of oxidative stress pathways. It is also a substrate for the enzyme UDP-glucose:vanillic acid glucosyltransferase, which catalyzes its formation from UDP-glucose and vanillic acid.
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| ln Vitro |
In vitro studies of Vanillic acid glucoside are limited. As a hydrolyzable tannin, it would be expected to have antioxidant activity, similar to other tannins. It is a natural product isolated from various plants and is used as a reference standard in analytical chemistry. However, specific in vitro potency data such as IC₅₀ values or assay results are not detailed in the available sources. Its primary use is as a research compound for phytochemical and analytical studies.
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| ln Vivo |
Specific in vivo activity data for Vanillic acid glucoside are not available in the consulted sources. As a hydrolyzable tannin found in food items such as sweet marjoram, orange bell pepper, and yellow bell pepper, it may contribute to the health benefits of these foods. However, no specific pharmacological in vivo studies have been reported. Its role as a plant metabolite suggests it may have physiological functions in plants.
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| Enzyme Assay |
No specific protocols for enzyme/receptor binding assays are available for Vanillic acid glucoside. As a natural product standard, it is typically used in chromatographic methods such as HPLC for quantitative analysis of vanillic acid derivatives in plant extracts. For biological activity testing, standard antioxidant assays such as DPPH and ABTS radical scavenging assays could be employed, but none have been reported for this specific compound.
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| Cell Assay |
No specific cell-based assay protocols are available for Vanillic acid glucoside. The compound is primarily used as an analytical standard and a reference compound for natural product research. For potential biological activity, standard cell viability or antioxidant assays could be employed using cell lines such as macrophages or endothelial cells, but none have been reported. Its use is limited to phytochemical and analytical applications.
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| Animal Protocol |
No specific in vivo animal experiment protocols are available for Vanillic acid glucoside. The compound is a natural product used as a reference standard and is not intended for in vivo pharmacological studies. No pharmacokinetic or efficacy studies in animal models have been reported. Its presence in food items suggests it is consumed orally, but specific studies have not been conducted.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for Vanillic acid glucoside are not available. As a glucoside with a molecular weight of 330.29 g/mol, it may be hydrolyzed in the intestine by glycosidases to release vanillic acid, which is known to be absorbed and metabolized. The compound is a natural product found in various plants and food items. However, detailed ADME parameters have not been characterized.
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| Toxicity/Toxicokinetics |
Toxicological data for Vanillic acid glucoside are limited. As a natural compound found in food items such as sweet marjoram and peppers, it is generally considered safe for consumption at dietary levels. However, comprehensive toxicological studies have not been reported. Standard laboratory safety precautions should be followed when handling the compound. It is intended for research use only.
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| Additional Infomation |
4-(β-D-glucopyranosyl)-3-methoxybenzoic acid is a tannin. It functions as a metabolite. It has been reported in Davallia trichomanoides, Picea glauca, and other organisms with relevant data.
Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside) is a hydrolyzable tannin and natural product isolated from Hypericum persica, Capsicum annuum, and other plants. It is a dimeric oxaloside and a glucoside of vanillic acid. The compound is used as a reference standard in analytical chemistry and phytochemical research. It is not approved for any clinical indication and is strictly a research compound. |
| Molecular Formula |
C14H18O9
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|---|---|
| Molecular Weight |
330.29
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| Exact Mass |
330.095
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| CAS # |
32142-31-7
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| PubChem CID |
14132337
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| Appearance |
Typically exists as solid at room temperature
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| LogP |
-1.5
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| Hydrogen Bond Donor Count |
5
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| Hydrogen Bond Acceptor Count |
9
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| Rotatable Bond Count |
5
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| Heavy Atom Count |
23
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| Complexity |
404
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| Defined Atom Stereocenter Count |
5
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| SMILES |
COC1=C(C=CC(=C1)C(=O)O)OC2C(C(C(C(O2)CO)O)O)O
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| InChi Key |
JYFOSWJYZIVJPO-YGEZULPYSA-N
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| InChi Code |
InChI=1S/C14H18O9/c1-21-8-4-6(13(19)20)2-3-7(8)22-14-12(18)11(17)10(16)9(5-15)23-14/h2-4,9-12,14-18H,5H2,1H3,(H,19,20)/t9-,10-,11+,12-,14-/m1/s1
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| Chemical Name |
3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.0276 mL | 15.1382 mL | 30.2764 mL | |
| 5 mM | 0.6055 mL | 3.0276 mL | 6.0553 mL | |
| 10 mM | 0.3028 mL | 1.5138 mL | 3.0276 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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