| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| Other Sizes |
| Targets |
D 131 is used as a photosensitizer in dye-sensitized solar cells (DSSCs) with high charge mobility and absorption coefficient. It does not have a biological target but is a chemical dye used in photophysical and materials science applications. It has excellent photoelectric conversion efficiency as a metal-free dye.
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|---|---|
| ln Vitro |
D 131 is an orange organic indoline dye with an absorption maximum at 425 nm. It is used in dye-sensitized solar cells as a photosensitizer. It has high charge mobility and absorption coefficient. It is a fluorescent dye reagent.
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| ln Vivo |
In vivo, D 131 is not used as a therapeutic agent. It is used in materials science and photophysical research. No biological applications are reported. It is a chemical dye for research use.
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| Enzyme Assay |
Cell-free assays for D 131: the compound is characterized by UV-Vis spectrophotometry to measure absorption maxima at 425 nm. Its photophysical properties, including fluorescence quantum yield and charge mobility, are measured using appropriate instrumentation. Purity is assessed by HPLC.
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| Cell Assay |
Cellular assays for D 131: cells are not typically treated with this dye as it is used in materials science. It may be used in imaging applications if conjugated to targeting moieties. Cytotoxicity would be assessed by MTT assay if cellular applications are pursued.
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| Animal Protocol |
In vivo animal studies for D 131: the compound is not administered to animals as a therapeutic agent. No specific pharmacological studies are reported. It is a research chemical for materials science.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of D 131: as a dye, it is not intended for systemic administration. No pharmacokinetics are applicable. Storage: powder at -20°C for up to 3 years.
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| Toxicity/Toxicokinetics |
Toxicity of D 131: comprehensive toxicity data are limited. As a dye, it may have toxicity if ingested or inhaled. It is for research use only. Standard laboratory safety precautions should be followed.
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| References |
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| Additional Infomation |
D 131 is a research compound used as an organic dye in dye-sensitized solar cells and photophysical studies. It is a fluorescent dye reagent. No clinical applications have been reported.
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| Molecular Formula |
C35H28N2O2
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|---|---|
| Molecular Weight |
508.61
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| Exact Mass |
508.215
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| CAS # |
652145-29-4
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| PubChem CID |
57937197
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| Appearance |
Typically exists as solid at room temperature
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| LogP |
8.119
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
6
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| Heavy Atom Count |
39
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| Complexity |
950
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| Defined Atom Stereocenter Count |
0
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| SMILES |
O([H])C(/C(/C#N)=C(\[H])/C1C([H])=C([H])C2=C(C=1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])N2C1C([H])=C([H])C(/C(/[H])=C(\C2C([H])=C([H])C([H])=C([H])C=2[H])/C2C([H])=C([H])C([H])=C([H])C=2[H])=C([H])C=1[H])=O
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| InChi Key |
GOTRYMLNXIJMCB-VFCFBJKWSA-N
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| InChi Code |
InChI=1S/C35H28N2O2/c36-23-28(35(38)39)20-25-16-19-34-32(22-25)30-12-7-13-33(30)37(34)29-17-14-24(15-18-29)21-31(26-8-3-1-4-9-26)27-10-5-2-6-11-27/h1-6,8-11,14-22,30,33H,7,12-13H2,(H,38,39)/b28-20+
|
| Chemical Name |
(E)-2-cyano-3-[4-[4-(2,2-diphenylethenyl)phenyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]indol-7-yl]prop-2-enoic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.9661 mL | 9.8307 mL | 19.6614 mL | |
| 5 mM | 0.3932 mL | 1.9661 mL | 3.9323 mL | |
| 10 mM | 0.1966 mL | 0.9831 mL | 1.9661 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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