| Size | Price | Stock | Qty |
|---|---|---|---|
| 25g |
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| Other Sizes |
| Targets |
Hexatriacontane has no specific biological target. As a saturated straight-chain hydrocarbon, it is inert and does not interact with biological receptors. It can act as a hydrophobic matrix component in model membrane studies but has no pharmacological activity. Its primary use is as an analytical standard for hydrocarbon analysis.
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|---|---|
| ln Vitro |
In cell-free assays, hexatriacontane is used as a non-polar standard for GC-MS calibration. It can be used to test the efficiency of hydrocarbon extraction methods or to study the partitioning of alkanes in organic phases. It has no inhibitory or activating effects on enzymes or receptors at relevant concentrations.
|
| ln Vivo |
No specific in vivo studies for hexatriacontane are available. Long-chain alkanes are generally poorly absorbed from the gastrointestinal tract and are excreted unchanged in feces. They are considered biologically inert. If absorbed, they may accumulate in adipose tissue but are not metabolized to a significant extent.
|
| Enzyme Assay |
For non-cell assays, hexatriacontane is analyzed by GC-FID or GC-MS. A sample is dissolved in hexane or chloroform (0.1-1 mg/mL) and 1 microL is injected onto a non-polar capillary column (e.g., DB-5). Temperature program: 100degC to 300degC at 10degC/min, hold for 10 minutes. Retention time is approximately 20-25 minutes. Calibration curves are prepared using known concentrations of the standard.
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| Cell Assay |
No cell-based assays for hexatriacontane are available. Due to its high hydrophobicity and inertness, it is unlikely to have significant cellular effects. It may be used as a control compound to confirm that observed cellular effects are not due to non-specific hydrophobic interactions. No cytotoxicity is expected at relevant concentrations.
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| Animal Protocol |
No animal models specific to hexatriacontane are available. For related alkanes, a typical toxicity study would involve oral administration to rodents at doses up to 5000 mg/kg to determine LD50. No significant toxicity is expected, and the compound would be excreted in feces.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for hexatriacontane is not available. Long-chain alkanes are poorly absorbed from the intestine due to their high hydrophobicity. Any absorbed fraction would likely be stored in adipose tissue and eliminated very slowly. It is not metabolized by common phase I or phase II enzymes. For research use, store at room temperature in a sealed container.
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| Toxicity/Toxicokinetics |
Toxicity Summary
Identification and Uses: Hexadecane is a higher n-alkane containing 36 carbon atoms (C36). Human Exposure and Toxicity: No data available. Animal Studies: No data available. Hexatriacontane has low acute toxicity. The oral LD50 is expected to be >5000 mg/kg. It may be a mild skin and eye irritant. Inhalation of dust may cause respiratory irritation. Chronic exposure is not associated with carcinogenicity or mutagenicity. It is not a hazardous substance under GHS classification. |
| Additional Infomation |
Hexatriacontane is an alkane containing 36 carbon atoms and having a straight-chain structure. It has been reported to exist in Madagascar vanilla (Vanilla madagascariensis), autumn datura (Mandragora autumnalis), and other organisms with relevant data.
Hexatriacontane is a research chemical, not an approved drug. It is used as an analytical standard for hydrocarbon analysis, including gas chromatography and mass spectrometry calibration. It is also used in the study of waxes, lubricants, and materials science. It is for laboratory use only and not for human consumption. |
| Molecular Formula |
C36H74
|
|---|---|
| Molecular Weight |
506.97
|
| Exact Mass |
506.579
|
| CAS # |
630-06-8
|
| PubChem CID |
12412
|
| Appearance |
Waxy solid
|
| Density |
0.7795
|
| Boiling Point |
265 °C1 mm Hg(lit.)
|
| Melting Point |
75.081 °C
|
| Flash Point |
497°C
|
| Index of Refraction |
1.4573
|
| LogP |
14.29
|
| Hydrogen Bond Donor Count |
0
|
| Rotatable Bond Count |
33
|
| Heavy Atom Count |
36
|
| Complexity |
312
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
C([H])([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
|
| InChi Key |
YDLYQMBWCWFRAI-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C36H74/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-36H2,1-2H3
|
| Chemical Name |
hexatriacontane
|
| Synonyms |
ALKANE C36
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.9725 mL | 9.8625 mL | 19.7250 mL | |
| 5 mM | 0.3945 mL | 1.9725 mL | 3.9450 mL | |
| 10 mM | 0.1973 mL | 0.9863 mL | 1.9725 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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