| Size | Price | Stock | Qty |
|---|---|---|---|
| 1mg |
|
||
| 5mg |
|
||
| Other Sizes |
| Targets |
10-Methyl lauric acid has no defined pharmacological drug target. It is a naturally occurring branched-chain fatty acid that can be incorporated into complex lipids. It may serve as a biochemical marker for certain bacterial species or for studying fatty acid metabolism, as branched-chain fatty acids are known to modulate membrane fluidity in bacteria. Its presence in insect secretions suggests a potential pheromonal role, but no direct human biological targets have been identified.
|
|---|---|
| ln Vitro |
In non-cell assays, 10-Methyl lauric acid is used as an analytical standard for the identification and quantification of branched-chain fatty acids by gas chromatography-mass spectrometry (GC-MS). It can be used in lipidomics research to profile fatty acid composition in bacterial or insect samples. No specific enzyme inhibition or receptor binding activity has been reported for this compound.
|
| ln Vivo |
No specific in vitro cell-based bioactivity data is available for 10-Methyl lauric acid. It is not a molecule with known inherent cellular activity in mammalian systems. It would be expected to be metabolized similarly to other medium-chain fatty acids via beta-oxidation. Any direct effects on cell viability, proliferation, or signaling would need to be determined experimentally.
|
| Enzyme Assay |
For a non-cell analytical assay, 10-Methyl lauric acid can be analyzed by GC-MS. A working solution is prepared by dissolving the compound in an organic solvent like hexane or ethyl acetate (e.g., 1 mg/mL). The sample is injected onto a non-polar capillary column (e.g., DB-5). A temperature gradient is applied (e.g., 100degC to 300degC at 10degC/min) to elute the compound, which is identified by its characteristic retention time and mass spectrum.
|
| Cell Assay |
No specific cell-based assays are performed with 10-Methyl lauric acid. Its activity could be investigated by treating a relevant cell line (e.g., hepatocytes or adipocytes) with the compound to study its effects on lipid metabolism. Cells would be treated with various concentrations (e.g., 1-100 uM) for 24-72 hours. Fatty acid oxidation rates could be measured by incubating cells with [3H]palmitate and quantifying the release of 3H2O.
|
| Animal Protocol |
No in vivo studies for 10-Methyl lauric acid are available. It is not a pharmacological or therapeutic agent. Studies would likely focus on its metabolism or its role as a biochemical marker. For example, it could be administered orally to rodents (e.g., 100-500 mg/kg) to study its absorption and incorporation into tissue lipids, with samples analyzed by GC-MS.
|
| ADME/Pharmacokinetics |
Pharmacokinetic data for 10-Methyl lauric acid is not available. As a medium-chain fatty acid, it is expected to be well absorbed from the gastrointestinal tract and metabolized through beta-oxidation pathways in the liver and other tissues. It is stored as a liquid at room temperature or as a powder at -20degC in a sealed, dry container.
|
| Toxicity/Toxicokinetics |
Specific toxicity data for 10-Methyl lauric acid is not available. Medium-chain fatty acids are generally considered safe and have low acute toxicity. As a fatty acid, it may be a mild skin and eye irritant. Standard laboratory safety practices for handling research chemicals should be followed. It is not intended for human consumption.
|
| References | |
| Additional Infomation |
10-Methyldodecanoic acid is a methyl branched fatty acid formed by replacing the methyl group at the 10-position of dodecanoic acid (lauric acid). It is a branched saturated fatty acid, a medium-chain fatty acid, and a methyl branched fatty acid. Its function is related to that of dodecanoic acid.
10-Methyldodecanoic acid has been reported to exist in Streptomyces, and relevant data are available for reference. 10-Methyl lauric acid is a research chemical and is not an FDA-approved drug. It has no clinical applications. It is used as an analytical standard for the identification of fatty acids in complex biological mixtures (e.g., bacterial extracts, insect pheromone studies) and as a building block in organic synthesis for the preparation of other branched-chain compounds. |
| Molecular Formula |
C13H26O2
|
|---|---|
| Molecular Weight |
214.34
|
| Exact Mass |
214.193
|
| CAS # |
7416-57-1
|
| PubChem CID |
3014565
|
| Appearance |
Typically exists as solids at room temperature
|
| Density |
0.9 g/cm3
|
| Boiling Point |
323.3ºC at 760 mmHg
|
| Flash Point |
176.7ºC
|
| Index of Refraction |
1.448
|
| LogP |
4.238
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
2
|
| Rotatable Bond Count |
10
|
| Heavy Atom Count |
15
|
| Complexity |
155
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CCC(C)CCCCCCCCC(=O)O
|
| InChi Key |
YETWOCQNUTWSQA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C13H26O2/c1-3-12(2)10-8-6-4-5-7-9-11-13(14)15/h12H,3-11H2,1-2H3,(H,14,15)
|
| Chemical Name |
10-methyldodecanoic acid
|
| Synonyms |
10-Methyl dodecanoic acid; FA 13:0
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.6655 mL | 23.3274 mL | 46.6548 mL | |
| 5 mM | 0.9331 mL | 4.6655 mL | 9.3310 mL | |
| 10 mM | 0.4665 mL | 2.3327 mL | 4.6655 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
