| Size | Price | Stock | Qty |
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| 500mg |
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| 1g |
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| 2g |
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| 5g |
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| 10g |
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| 25g |
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| 50g |
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| Other Sizes |
Purity: ≥98%
| Targets |
Phosphoethanolamine calcium does not have a specific drug target like an enzyme or receptor. It is a biochemical reagent and a component of cell membranes. As a phospholipid component, it plays a structural role in maintaining cell membrane integrity and function. Phosphoethanolamine is the precursor of phosphatidylethanolamine and can be used for the synthesis of phosphatidylcholine.
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| ln Vitro |
Phosphoethanolamine calcium is used to construct glycerophospholipids and sphingomyelin. It is a component of phosphatidylethanolamine, which is the most abundant phospholipid in cell membranes. Phosphorylethanolamine has been studied for potential anticancer activities, though specific in vitro activity data is limited. Phosphoethanolamine (calcium) is used in the study of phospholipid metabolism and cell membrane structure.
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| ln Vivo |
In vivo activity for Phosphoethanolamine calcium is not well-documented. As a biochemical reagent and membrane component, it is not typically evaluated as a therapeutic agent in animal models. Its potential anticancer activities would require further investigation. Ca-AEP has been shown to help maintain cell membrane integrity.
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| Enzyme Assay |
Specific protocols for enzyme/receptor binding assays are not applicable for Phosphoethanolamine calcium. It does not function as an enzyme inhibitor or receptor ligand. Its interactions are studied in the context of membrane biochemistry and lipid metabolism.
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| Cell Assay |
Cellular assays for Phosphoethanolamine calcium are not standard. As a biochemical reagent, it may be used in cell culture media or in studies of lipid metabolism and membrane biology. Its effects on cell function would be related to its role as a membrane component.
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| Animal Protocol |
In vivo animal model protocols for Phosphoethanolamine calcium are not established. As a biochemical reagent, it is not typically administered to animal models for therapeutic evaluation.
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| ADME/Pharmacokinetics |
Specific pharmacokinetic data for Phosphoethanolamine calcium is not available. As a biochemical reagent and membrane component, its pharmacokinetic properties are not typically studied.
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| Toxicity/Toxicokinetics |
Specific toxicological data for Phosphoethanolamine calcium is not available. As a biochemical reagent, standard safety precautions for handling chemicals should be followed. Limited information suggests it is a component of biological membranes and is likely to have low toxicity.
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| References |
Biochimie. 2016 Nov;130:81-90.
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| Additional Infomation |
Phosphoethanolamine calcium is a biochemical reagent used in research. It is not a drug and is not approved for clinical use. It is used in studies of membrane biology, lipid metabolism, and as a component of affinity chromatography media. Phosphoethanolamines are important components of the human cell membrane structure, which help to maintain the integrity of the cell membrane and improve cell function.
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| Molecular Formula |
C2H6CANO4P
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|---|---|
| Molecular Weight |
179.1248
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| Exact Mass |
178.966
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| CAS # |
10389-08-9
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| Related CAS # |
1071-23-4;10389-08-9 (calcium);
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| PubChem CID |
19985431
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| Appearance |
Typically exists as solid at room temperature
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| LogP |
0.631
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
5
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
9
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| Complexity |
86.7
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
SYLKQIHLJRQWAY-UHFFFAOYSA-L
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| InChi Code |
InChI=1S/C2H8NO4P.Ca/c3-1-2-7-8(4,5)6/h1-3H2,(H2,4,5,6)/q+2/p-2
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| Chemical Name |
Calcium 2-aminoethyl phosphate
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| Synonyms |
Phosphoethanolamine calcium Calcium 2-aminoethylphosphate,
Ca-AEP or Ca-2AEP calcium EAP Phosphorylcolamine calcium Colamine
phosphate Ethanolamine phosphate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.5828 mL | 27.9142 mL | 55.8285 mL | |
| 5 mM | 1.1166 mL | 5.5828 mL | 11.1657 mL | |
| 10 mM | 0.5583 mL | 2.7914 mL | 5.5828 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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