| Size | Price | Stock | Qty |
|---|---|---|---|
| 1mg |
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| 100mg | |||
| Other Sizes |
| Targets |
The molecular targets of Perisesaccharide C have not been fully elucidated in the published literature. As an oligosaccharide isolated from Periploca sepium, a plant used in traditional medicine, Perisesaccharide C may have various biological activities. Periploca sepium is known to contain compounds with cardiotonic, anti-inflammatory, and immunomodulatory activities. Oligosaccharides in general can interact with cell surface receptors, modulate immune function, and affect gut microbiota. However, specific targets for Perisesaccharide C have not been identified. The compound is primarily used as a phytochemical reference standard and for studying the chemistry of Periploca sepium. Further research is needed to identify the molecular targets and mechanisms of action of Perisesaccharide C.
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| ln Vitro |
In vitro activity of Perisesaccharide C has not been extensively characterized in the published literature. As an oligosaccharide isolated from Periploca sepium, the compound may have biological activities including immunomodulatory, anti-inflammatory, or antioxidant effects. However, specific in vitro activity data for Perisesaccharide C have not been widely reported. The compound is primarily used as a phytochemical reference standard for analytical and identification purposes. Studies on the biological activities of Periploca sepium extracts have reported various effects, but the specific contribution of Perisesaccharide C to these activities has not been determined. Further research is needed to characterize the in vitro activity of this compound.
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| ln Vivo |
In vivo activity of Perisesaccharide C has not been characterized in the published literature. As an oligosaccharide isolated from Periploca sepium, the compound may have pharmacological activities, but specific in vivo studies have not been reported. The compound is primarily used as a research tool for phytochemical studies rather than as a therapeutic candidate. Periploca sepium has been used in traditional medicine, and extracts of the plant have shown various pharmacological activities, but the specific contribution of Perisesaccharide C to these activities has not been determined. Further research is needed to evaluate the in vivo activity of this compound.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays are not standard for Perisesaccharide C, as the compound is an oligosaccharide with no established enzyme or receptor targets. However, the compound's structure and properties can be characterized using analytical chemistry methods. High-performance liquid chromatography (HPLC) and mass spectrometry are used to verify the molecular weight (752.84 g/mol) and chemical composition (C35H60O17). The compound's purity (≥98%) is confirmed by HPLC and NMR analysis. Stability studies may be performed by incubating Perisesaccharide C in various buffer systems and analyzing degradation products over time. The compound's oligosaccharide structure can be characterized by NMR spectroscopy and mass spectrometry. Specific binding assays have not been reported for this compound.
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| Cell Assay |
In vitro cellular assays for Perisesaccharide C have not been extensively reported in the published literature. As an oligosaccharide isolated from Periploca sepium, the compound may have effects on cell proliferation, immune function, or other cellular processes. However, specific cellular assays for Perisesaccharide C have not been widely described. The compound is primarily used as a phytochemical reference standard. If cellular assays were to be performed, appropriate cell lines would be selected based on the compound's suspected biological activities. Cytotoxicity would be assessed using standard viability assays. Further research is needed to characterize the cellular effects of Perisesaccharide C.
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| Animal Protocol |
In vivo animal studies for Perisesaccharide C have not been reported in the published literature. As a research chemical isolated from Periploca sepium, the compound has not been evaluated in animal models of disease. The compound is primarily used as a phytochemical reference standard and for analytical purposes. If in vivo studies were to be conducted, appropriate animal models would be selected based on the compound's suspected biological activities. Standard endpoints would include assessment of efficacy, pharmacokinetics, and toxicity. Further research is needed to evaluate the in vivo activity of Perisesaccharide C.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of Perisesaccharide C have not been characterized in the published literature. The compound has a molecular formula of C35H60O17 and a molecular weight of 752.84 g/mol. As an oligosaccharide, Perisesaccharide C would be expected to have limited oral bioavailability due to its size and polarity. The compound may be metabolized by intestinal microbiota or hydrolyzed by glycosidases. Comprehensive pharmacokinetic parameters including half-life, volume of distribution, clearance, and bioavailability have not been reported. The compound's stability in solution and under various storage conditions has been characterized. Further pharmacokinetic studies are needed to understand the absorption, distribution, metabolism, and elimination of Perisesaccharide C.
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| Toxicity/Toxicokinetics |
Perisesaccharide C is intended for laboratory research use only and has not undergone comprehensive toxicology testing. As a naturally occurring oligosaccharide, the compound may have a favorable safety profile, but specific toxicity data have not been reported. Standard in vitro cytotoxicity assays would be needed to assess the compound's toxicity in cell culture. In vivo, animals would be monitored for signs of toxicity if the compound were to be evaluated in animal studies. Comprehensive toxicological characterization including genotoxicity, cardiotoxicity, and repeated-dose toxicity studies has not been reported. The compound is not approved for human use and is strictly intended for research purposes.
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| References | |
| Additional Infomation |
Perisesaccharide C is an oligosaccharide isolated from the root barks of Periploca sepium, a medicinal plant used in traditional Chinese medicine. It is also reported to be extracted from the roots of Salix truncatula. The compound has a molecular formula of C35H60O17 and a molecular weight of 752.84 g/mol. Perisesaccharide C is available as a research-grade compound with high purity (≥98% by HPLC). The compound is primarily used as a phytochemical reference standard for analytical and identification purposes. The biological activities and molecular targets of Perisesaccharide C have not been fully characterized. Perisesaccharide C has not entered clinical trials and has not received regulatory approval for any indication. It is available from research chemical suppliers for non-clinical research purposes only. Perisesaccharide C is a valuable research tool for studying the chemistry and pharmacology of Periploca sepium.
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| Molecular Formula |
C35H60O17
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|---|---|
| Molecular Weight |
752.841
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| Exact Mass |
752.383
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| CAS # |
1311473-28-5
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| PubChem CID |
124928615
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| Appearance |
White to off-white solid powder
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| Density |
1.3±0.1 g/cm3
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| Boiling Point |
814.4±65.0 °C at 760 mmHg
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| Flash Point |
243.0±27.8 °C
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| Vapour Pressure |
0.0±6.6 mmHg at 25°C
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| Index of Refraction |
1.523
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| LogP |
2.51
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| Hydrogen Bond Donor Count |
2
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| Hydrogen Bond Acceptor Count |
17
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| Rotatable Bond Count |
13
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| Heavy Atom Count |
52
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| Complexity |
1120
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| Defined Atom Stereocenter Count |
20
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| SMILES |
C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2OC)O[C@@H]3[C@H](O[C@H](C[C@@H]3OC)O[C@@H]4[C@H](O[C@H](C[C@@H]4OC)O[C@@H]5[C@H](OC(=O)C[C@H]5OC)C)C)C)C)O)OC)O
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| InChi Key |
DIJQVVFCZUGNFK-IELQLYKTSA-N
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| InChi Code |
InChI=1S/C35H60O17/c1-15-28(37)34(43-10)29(38)35(48-15)52-33-19(5)47-27(14-23(33)42-9)51-32-18(4)46-26(13-22(32)41-8)50-31-17(3)45-25(12-21(31)40-7)49-30-16(2)44-24(36)11-20(30)39-6/h15-23,25-35,37-38H,11-14H2,1-10H3/t15-,16-,17-,18-,19-,20-,21+,22+,23+,25+,26+,27+,28+,29-,30-,31-,32-,33-,34+,35+/m1/s1
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| Chemical Name |
(4R,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,3R,4S,5S,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-one
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.3283 mL | 6.6415 mL | 13.2830 mL | |
| 5 mM | 0.2657 mL | 1.3283 mL | 2.6566 mL | |
| 10 mM | 0.1328 mL | 0.6642 mL | 1.3283 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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