| Size | Price | Stock | Qty |
|---|---|---|---|
| 1mg |
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| 5mg |
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| Other Sizes |
| Targets |
Pelargonidin chloride acts as a scavenger of nitric oxide free radicals and has antioxidant effects. Like other polyphenolics, it has significant antioxidant activity. It has a role as a phytoestrogen and a plant metabolite.
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|---|---|
| ln Vitro |
In vitro, Pelargonidin chloride is a scavenger of nitric oxide free radicals and has antioxidant effects. It has significant antioxidant activity. Specific IC50 or EC50 values are not provided in the available sources.
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| ln Vivo |
In vivo activity data for Pelargonidin chloride are not extensively detailed in the available sources. As a natural polyphenolic compound, it has antioxidant properties. Specific in vivo efficacy data have not been reported.
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| Enzyme Assay |
The in vitro antioxidant assay for Pelargonidin chloride involves measuring its ability to scavenge free radicals, such as nitric oxide. The compound is incubated with a radical-generating system, and the reduction in radical levels is measured using colorimetric or fluorescence-based methods.
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| Cell Assay |
Cellular assays for Pelargonidin chloride are performed using cell lines exposed to oxidative stress. Cells are treated with the compound, and markers of oxidative stress (e.g., reactive oxygen species) are measured.
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| Animal Protocol |
In vivo animal studies for Pelargonidin chloride are not detailed in the available sources. The compound is a natural product with antioxidant properties. Specific animal models and dosing regimens have not been described.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for Pelargonidin chloride are not available in the provided sources. The compound has a molecular weight of 306.70 g/mol. It should be stored at 2-8°C.
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| Toxicity/Toxicokinetics |
Toxicity data for Pelargonidin chloride are not reported in the available sources. As a naturally occurring compound, it is generally considered to have a favorable safety profile, but specific toxicological studies have not been described.
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| References | |
| Additional Infomation |
Pelargonidin chloride is an anthocyanin chloride whose cationic counterpart is Pelargonidin. It is a phytoestrogen and plant metabolite containing Pelargonidin molecules.
Pelargonidin chloride is a natural polyphenolic anthocyanidin with antioxidant activity. It is a scavenger of nitric oxide free radicals. The compound is available from commercial suppliers for research purposes. |
| Molecular Formula |
C15H11CLO5
|
|---|---|
| Molecular Weight |
306.6978
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| Exact Mass |
306.029
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| CAS # |
134-04-3
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| Related CAS # |
7690-51-9 (Parent)
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| PubChem CID |
67249
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| Appearance |
Light brown to brown solid powder
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| LogP |
0.207
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| Hydrogen Bond Donor Count |
4
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| Hydrogen Bond Acceptor Count |
5
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
21
|
| Complexity |
328
|
| Defined Atom Stereocenter Count |
0
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| InChi Key |
YPVZJXMTXCOTJN-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C15H10O5.ClH/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15;/h1-7H,(H3-,16,17,18,19);1H
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| Chemical Name |
2-(4-hydroxyphenyl)chromenylium-3,5,7-triol;chloride
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.2605 mL | 16.3026 mL | 32.6052 mL | |
| 5 mM | 0.6521 mL | 3.2605 mL | 6.5210 mL | |
| 10 mM | 0.3261 mL | 1.6303 mL | 3.2605 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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