| Size | Price | Stock | Qty |
|---|---|---|---|
| 100g |
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| Other Sizes |
| Targets |
Naphthol Green B does not have a specific biological target. It is an iron-complex dye used as a colorimetric reagent and stain. It can be used to make electrochemical sensors for detecting H2O2. In histology, it is used for microscopy and complexometry. Its mechanism of action is based on its chemical properties as a dye rather than engagement with a biological target.
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| ln Vitro |
In vitro, Naphthol Green B is used as a dye for various applications. It is suitable for microscopy and complexometry. It can be used for wool dyeing, silk dyeing, and polyamide dyeing. It may be utilized to make electrochemical sensors for detecting H2O2. Specific pharmacological activity data, such as IC50 values, are not applicable as it is a dye rather than a pharmacologically active compound.
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| ln Vivo |
In vivo applications of Naphthol Green B are not typical, as it is primarily a dye used in vitro and for industrial applications. It is not administered to living organisms for therapeutic or diagnostic purposes. Its use is confined to laboratory and industrial settings.
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| Enzyme Assay |
A cell-free assay for Naphthol Green B is not applicable as it is not an enzyme inhibitor. Its properties as a dye are characterized by spectroscopic methods. Its use in electrochemical sensors involves measuring its electrochemical properties in the presence of H2O2.
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| Cell Assay |
Cellular experiments with Naphthol Green B are not typical, as it is used as a dye in histology and microscopy rather than in cell-based assays. It can be used to stain cells or tissues for microscopic examination.
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| Animal Protocol |
In vivo animal experiments for Naphthol Green B are not applicable, as it is a dye used in vitro and for industrial purposes.
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| ADME/Pharmacokinetics |
Naphthol Green B has a molecular formula of C30H15FeN3Na3O15S3 and a molecular weight of 878.46 g/mol. Its CAS number is 19381-50-1. It is a dark green powder that is soluble in water. Specific pharmacokinetic properties are not applicable as it is not a therapeutic drug. For storage, it should be kept in a cool, dry place.
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| Toxicity/Toxicokinetics |
Toxicity data for Naphthol Green B are not provided in the available sources. As a dye, it should be handled with appropriate safety precautions. It is intended for research and industrial use only and is not for human consumption.
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| References | |
| Additional Infomation |
Naphthol Green B is an organosodium salt composed of iron (3+), sodium, and 5-(oxide-imino)-6-oxo-5,6-dihydronaphthyl-2-sulfonate ions in a 1:1:3 ratio. It is used for staining collagen and animal tissues and is a histological dye. It is an organosodium salt and also an iron coordination compound. It contains 5-(oxide-imino)-6-oxo-5,6-dihydronaphthyl-2-sulfonate ions.
Naphthol Green B (CAS: 19381-50-1) is an iron-complex dye. Its synonyms include Acid Green 1 and C.I. 10020. The compound is used for microscopy, complexometry, and as a dye for textiles. It can also be used to make electrochemical sensors. It is not a therapeutic drug and is strictly for research and industrial purposes. |
| Molecular Formula |
C30H18FEN3NA3O15S3
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|---|---|
| Molecular Weight |
881.4843
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| Exact Mass |
877.871
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| CAS # |
19381-50-1
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| PubChem CID |
6915910
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| Appearance |
Brown to black solid powder
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| LogP |
9.194
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
18
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| Rotatable Bond Count |
0
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| Heavy Atom Count |
55
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| Complexity |
377
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
JMXROTHPANUTOJ-UHFFFAOYSA-H
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| InChi Code |
InChI=1S/3C10H7NO5S.Fe.3Na/c3*12-9-4-1-6-5-7(17(14,15)16)2-3-8(6)10(9)11-13;;;;/h3*1-5,12H,(H,14,15,16);;;;/q;;;+3;3*+1/p-6
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| Chemical Name |
trisodium;iron(3+);5-nitroso-6-oxidonaphthalene-2-sulfonate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.1345 mL | 5.6723 mL | 11.3446 mL | |
| 5 mM | 0.2269 mL | 1.1345 mL | 2.2689 mL | |
| 10 mM | 0.1134 mL | 0.5672 mL | 1.1345 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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