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Mudanpioside C

Cat No.:V39896 Purity: ≥98%
Mudanpioside C is a polyterpenoid developed from the peony plant.
Mudanpioside C
Mudanpioside C Chemical Structure CAS No.: 172760-03-1
Product category: New2
This product is for research use only, not for human use. We do not sell to patients.
Size Price Stock Qty
5mg
10mg
100mg
Other Sizes
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Product Description
Mudanpioside C is a polyterpenoid developed from the peony plant.
Mudanpioside C (CAS#: 172760-03-1) is a naturally occurring monoterpenoid compound isolated from the root of Paeonia lactiflora Pall. (peony plant) and the root bark of Paeonia suffruticosa (Cortex Moutan). With the molecular formula C30H32O13 and a molecular weight of 600.57, Mudanpioside C is a monoterpene glycoside. It is a natural product used in research to study the pharmacological activities of compounds from traditional Chinese medicinal herbs.
Biological Activity I Assay Protocols (From Reference)
Targets
Mudanpioside C does not have a well-defined single pharmacological target, as it is a natural monoterpenoid with complex biological activities. It is a component of peony plants, which are used in traditional Chinese medicine for their anti-inflammatory, analgesic, and immunomodulatory properties. Mudanpioside C may contribute to these effects, but its specific molecular targets have not been fully characterized. The compound's mechanisms of action may involve modulation of inflammatory pathways, antioxidant activity, or regulation of immune responses.
ln Vitro
Mudanpioside C does not possess significant pharmacological activity as a pure compound in typical in vitro assays, as it is a natural product with complex biological activities. Studies on Mudanpioside C typically involve evaluating its anti-inflammatory, antioxidant, or immunomodulatory effects in cellular models. However, detailed in vitro activity data for Mudanpioside C specifically are limited, as most studies focus on the peony plant extracts or other related compounds.
ln Vivo
In vivo activity of Mudanpioside C is related to its role as a component of peony plants, which are used in traditional Chinese medicine. Peony extracts have been shown to have anti-inflammatory, analgesic, and immunomodulatory effects in animal models and clinical studies. However, the specific in vivo effects of Mudanpioside C as an isolated compound have not been extensively characterized. Most studies focus on the plant extracts, which contain multiple compounds including Mudanpioside C.
Enzyme Assay
In vitro enzyme/receptor binding experiments for Mudanpioside C are not typical, as it is a natural product with complex biological activities rather than a well-defined pharmacologically active compound. Studies may involve measuring its antioxidant activity, anti-inflammatory effects, or immunomodulatory effects in cell-based assays. The compound can also be used as a reference standard in analytical chemistry for the identification and quantification of monoterpenoids in plant extracts. Its chemical properties are characterized using standard analytical methods such as HPLC and mass spectrometry.
Cell Assay
In vitro cellular experiments for Mudanpioside C typically involve studying its effects on inflammatory responses, oxidative stress, or immune function in cell lines. Cells are treated with the compound, and the production of inflammatory mediators, reactive oxygen species, or cytokines is measured. The compound's effects on cell viability and proliferation are also assessed. The anti-inflammatory, antioxidant, or immunomodulatory activities of Mudanpioside C are evaluated in these cellular models. However, detailed studies on Mudanpioside C specifically are limited.
Animal Protocol
In vivo animal experiments for Mudanpioside C are not typical, as it is a natural product component rather than a drug candidate. However, studies may involve administering peony extracts or their components to animals to evaluate their anti-inflammatory, analgesic, or immunomodulatory effects. The effects of Mudanpioside C as an individual compound have not been extensively studied in vivo.
ADME/Pharmacokinetics
Pharmacokinetic properties of Mudanpioside C have not been extensively characterized, as it is a natural product component rather than a drug candidate. With a molecular weight of 600.57 and complex glycoside structure, Mudanpioside C is expected to have poor oral bioavailability and may be poorly absorbed from the gastrointestinal tract. Detailed studies on its absorption, distribution, metabolism, and excretion are limited. Most pharmacokinetic studies focus on the plant extracts rather than the individual compounds.
Toxicity/Toxicokinetics
Toxicological data for Mudanpioside C are limited, as it is a natural product component rather than a drug candidate. Standard safety precautions for handling natural products apply, including the use of personal protective equipment and working in a well-ventilated area. The compound is not intended for human consumption. Its toxicity profile has not been extensively characterized.
Additional Infomation
Reports indicate that peony contains [(1R,2S,3S,5S,6R,8S)-3-[(2S,3R,4S,5S,6R)-6-(benzoyloxymethyl)-3,4,5-trihydroxyoxacyclohexane-2-yl]oxy-6-hydroxy-8-methyl-9,10-dioxacyclohexanetetracyclo[4.3.1.02,5.03,8]decane-2-yl]methyl4-hydroxybenzoic acid, and related data have been reported.
Mudanpioside C is a research compound that has not entered clinical trials or received regulatory approval for therapeutic use. It is a component of peony plants, which are used in traditional Chinese medicine for their anti-inflammatory, analgesic, and immunomodulatory properties. Mudanpioside C is used in research to study the pharmacological activities of monoterpenoids and to understand the active principles of traditional medicinal herbs. Further research is needed to fully elucidate its biological activities and potential therapeutic applications.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Physicochemical Properties
Molecular Formula
C30H32O13
Molecular Weight
600.567290306091
Exact Mass
600.184
CAS #
172760-03-1
PubChem CID
11801727
Appearance
White to off-white solid powder
Density
1.6±0.1 g/cm3
Boiling Point
789.1±60.0 °C at 760 mmHg
Flash Point
258.6±26.4 °C
Vapour Pressure
0.0±2.9 mmHg at 25°C
Index of Refraction
1.699
LogP
5.22
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
13
Rotatable Bond Count
10
Heavy Atom Count
43
Complexity
1110
Defined Atom Stereocenter Count
10
SMILES
C[C@]12C[C@@]3([C@@H]4C[C@]1([C@@]4(C(O2)O3)COC(=O)C5=CC=CC=C5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)COC(=O)C7=CC=C(C=C7)O)O)O)O)O
InChi Key
HMSMTLNPCAHHGP-IPRVBXPUSA-N
InChi Code
InChI=1S/C30H32O13/c1-27-13-29(37)19-11-30(27,28(19,26(42-27)43-29)14-39-24(36)15-5-3-2-4-6-15)41-25-22(34)21(33)20(32)18(40-25)12-38-23(35)16-7-9-17(31)10-8-16/h2-10,18-22,25-26,31-34,37H,11-14H2,1H3/t18-,19-,20-,21+,22-,25+,26?,27+,28+,29-,30+/m1/s1
Chemical Name
[(2R,3S,4S,5R,6S)-6-[[(2S,3R,5R,6R,8S)-2-(benzoyloxymethyl)-6-hydroxy-8-methyl-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methyl 4-hydroxybenzoate
HS Tariff Code
2934.99.9001
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light.
Shipping Condition
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
Solubility Data
Solubility (In Vitro)
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
Solubility (In Vivo)
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.

Injection Formulations
(e.g. IP/IV/IM/SC)
Injection Formulation 1: DMSO : Tween 80: Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution 50 μL Tween 80 850 μL Saline)
*Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution.
Injection Formulation 2: DMSO : PEG300Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO 400 μLPEG300 50 μL Tween 80 450 μL Saline)
Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO 900 μL Corn oil)
Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals).
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Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO 900 μL (20% SBE-β-CD in saline)]
*Preparation of 20% SBE-β-CD in Saline (4°C,1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution.
Injection Formulation 5: 2-Hydroxypropyl-β-cyclodextrin : Saline = 50 : 50 (i.e. 500 μL 2-Hydroxypropyl-β-cyclodextrin 500 μL Saline)
Injection Formulation 6: DMSO : PEG300 : castor oil : Saline = 5 : 10 : 20 : 65 (i.e. 50 μL DMSO 100 μLPEG300 200 μL castor oil 650 μL Saline)
Injection Formulation 7: Ethanol : Cremophor : Saline = 10: 10 : 80 (i.e. 100 μL Ethanol 100 μL Cremophor 800 μL Saline)
Injection Formulation 8: Dissolve in Cremophor/Ethanol (50 : 50), then diluted by Saline
Injection Formulation 9: EtOH : Corn oil = 10 : 90 (i.e. 100 μL EtOH 900 μL Corn oil)
Injection Formulation 10: EtOH : PEG300Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL EtOH 400 μLPEG300 50 μL Tween 80 450 μL Saline)


Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium)
Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose
Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals).
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Oral Formulation 3: Dissolved in PEG400
Oral Formulation 4: Suspend in 0.2% Carboxymethyl cellulose
Oral Formulation 5: Dissolve in 0.25% Tween 80 and 0.5% Carboxymethyl cellulose
Oral Formulation 6: Mixing with food powders


Note: Please be aware that the above formulations are for reference only. InvivoChem strongly recommends customers to read literature methods/protocols carefully before determining which formulation you should use for in vivo studies, as different compounds have different solubility properties and have to be formulated differently.

 (Please use freshly prepared in vivo formulations for optimal results.)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 1.6651 mL 8.3254 mL 16.6508 mL
5 mM 0.3330 mL 1.6651 mL 3.3302 mL
10 mM 0.1665 mL 0.8325 mL 1.6651 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.

Calculator

Molarity Calculator allows you to calculate the mass, volume, and/or concentration required for a solution, as detailed below:

  • Calculate the Mass of a compound required to prepare a solution of known volume and concentration
  • Calculate the Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Calculate the Concentration of a solution resulting from a known mass of compound in a specific volume
An example of molarity calculation using the molarity calculator is shown below:
What is the mass of compound required to make a 10 mM stock solution in 5 ml of DMSO given that the molecular weight of the compound is 350.26 g/mol?
  • Enter 350.26 in the Molecular Weight (MW) box
  • Enter 10 in the Concentration box and choose the correct unit (mM)
  • Enter 5 in the Volume box and choose the correct unit (mL)
  • Click the “Calculate” button
  • The answer of 17.513 mg appears in the Mass box. In a similar way, you may calculate the volume and concentration.

Dilution Calculator allows you to calculate how to dilute a stock solution of known concentrations. For example, you may Enter C1, C2 & V2 to calculate V1, as detailed below:

What volume of a given 10 mM stock solution is required to make 25 ml of a 25 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=25 μM, V2=25 ml and V1 is the unknown:
  • Enter 10 into the Concentration (Start) box and choose the correct unit (mM)
  • Enter 25 into the Concentration (End) box and select the correct unit (mM)
  • Enter 25 into the Volume (End) box and choose the correct unit (mL)
  • Click the “Calculate” button
  • The answer of 62.5 μL (0.1 ml) appears in the Volume (Start) box
g/mol

Molecular Weight Calculator allows you to calculate the molar mass and elemental composition of a compound, as detailed below:

Note: Chemical formula is case sensitive: C12H18N3O4  c12h18n3o4
Instructions to calculate molar mass (molecular weight) of a chemical compound:
  • To calculate molar mass of a chemical compound, please enter the chemical/molecular formula and click the “Calculate’ button.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
  • Molecular mass (or molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
  • Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
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Reconstitution Calculator allows you to calculate the volume of solvent required to reconstitute your vial.

  • Enter the mass of the reagent and the desired reconstitution concentration as well as the correct units
  • Click the “Calculate” button
  • The answer appears in the Volume (to add to vial) box
In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal to make allowance for loss during the experiment)
Step 2: Enter in vivo formulation (This is only a calculator, not the exact formulation for a specific product. Please contact us first if there is no in vivo formulation in the solubility section.)
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Calculation results

Working concentration mg/mL;

Method for preparing DMSO stock solution mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation:Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
             (2) Be sure to add the solvent(s) in order.

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