| Size | Price | Stock | Qty |
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| 100mg |
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| 250mg |
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| 500mg |
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| Other Sizes |
| Targets |
As a dipeptide building block, L-Lysyl-L-lysine diHCl does not have a direct biological target. Its utility lies in its role as an enzyme-cleavable linker in various biochemical applications. The compound consists of two lysine residues linked by a peptide bond. Lysine is a basic amino acid that plays important roles in protein structure and function. The dipeptide can be used to deliver biologically active peptides and as a building block for more complex molecules.
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| ln Vitro |
As a synthetic building block, L-Lysyl-L-lysine diHCl does not have direct in vitro biological activity. Its value is as a dipeptide linker and building block for peptide synthesis and biochemical research. The compound's in vitro activity would be evaluated indirectly through the biological activity of compounds synthesized using it. The compound itself is not typically tested in biological assays but is used as a reagent in chemical synthesis and biochemical research.
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| ln Vivo |
As a synthetic building block, L-Lysyl-L-lysine diHCl does not have in vivo biological activity. Its value is as a research tool for peptide delivery and biochemical applications. The compound is not intended for administration to animals or humans as a therapeutic. Its biological relevance is indirect, through the compounds that are synthesized using it.
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| Enzyme Assay |
In vitro enzyme assays may use L-Lysyl-L-lysine diHCl as a substrate for proteolytic enzymes that cleave the peptide bond between lysine residues. The compound can be used to study enzyme activity and specificity. It can also be used in peptide synthesis as a building block. Researchers should consult primary literature for specific assay protocols.
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| Cell Assay |
Cell culture experiments using L-Lysyl-L-lysine diHCl may involve its use as a supplement in cell culture media or as a component of peptide delivery systems. The compound's high solubility and stability make it valuable in various biochemical applications. However, specific cell-based assay protocols are not extensively documented.
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| Animal Protocol |
In vivo animal experiments are not extensively documented for L-Lysyl-L-lysine diHCl. As a dipeptide, it could potentially be used in studies of peptide delivery or metabolic disorders. However, specific in vivo protocols are limited. The compound is primarily used as a research reagent.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of L-Lysyl-L-lysine diHCl are not extensively characterized. The compound has molecular weight 347.28 and molecular formula C12H28Cl2N4O3. It is characterized by high solubility and stability. Storage: 4°C, protect from light, stored under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
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| Toxicity/Toxicokinetics |
No comprehensive toxicology data are available for L-Lysyl-L-lysine diHCl as it is a research reagent rather than a therapeutic agent. The compound is not intended for human use, and comprehensive toxicology studies have not been conducted. The compound should be handled with appropriate safety precautions as a chemical reagent. The compound is for research use only and is not for human use.
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| Additional Infomation |
L-Lysyl-L-lysine diHCl has CAS number 52123-30-5, molecular formula C12H28Cl2N4O3, and molecular weight 347.28. Synonyms: L-Lysyl-L-lysine dihydrochloride. It is a dipeptide compound formed by the coupling of two L-lysine molecules. It is an enzymatically cleaved basic amino acid that may be utilized to deliver biologically active peptides. Purity: typically ≥98%. Storage: 4°C, protect from light, stored under nitrogen. Not for human use; for research purposes only.
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| Molecular Formula |
C12H26N4O3.2[HCL]
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|---|---|
| Molecular Weight |
347.28172
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| Exact Mass |
346.154
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| CAS # |
52123-30-5
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| PubChem CID |
22852123
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| Appearance |
White to off-white solid powder
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| LogP |
3.236
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| Hydrogen Bond Donor Count |
7
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| Hydrogen Bond Acceptor Count |
6
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| Rotatable Bond Count |
11
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| Heavy Atom Count |
21
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| Complexity |
274
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| Defined Atom Stereocenter Count |
2
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| SMILES |
NCCCC[C@H](N)C(N[C@H](C(O)=O)CCCCN)=O.Cl.Cl
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| InChi Key |
LXQFWEBCTJENGB-BZDVOYDHSA-N
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| InChi Code |
InChI=1S/C12H26N4O3.2ClH/c13-7-3-1-5-9(15)11(17)16-10(12(18)19)6-2-4-8-14;;/h9-10H,1-8,13-15H2,(H,16,17)(H,18,19);2*1H/t9-,10-;;/m0../s1
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| Chemical Name |
(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoic acid;dihydrochloride
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage. (2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O : ≥ 100 mg/mL (~287.95 mM)
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.8795 mL | 14.3976 mL | 28.7952 mL | |
| 5 mM | 0.5759 mL | 2.8795 mL | 5.7590 mL | |
| 10 mM | 0.2880 mL | 1.4398 mL | 2.8795 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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