| Size | Price | Stock | Qty |
|---|---|---|---|
| 50mg |
|
||
| 100mg |
|
||
| 250mg |
|
||
| 500mg | |||
| Other Sizes |
| Targets |
Imidacloprid-urea does not have a specific biological target as a pharmacological agent. It is a secondary metabolite of the insecticide imidacloprid. Imidacloprid itself targets the nicotinic acetylcholine receptor in insects. Imidacloprid-urea is a breakdown product formed from the parent compound and is used as a marker for imidacloprid exposure in environmental samples.
|
|---|---|
| ln Vitro |
In vitro, Imidacloprid-urea is used as an analytical standard. It is not a pharmacologically active compound and does not have specific activity data, such as IC50 values. Its utility is in the detection and quantification of imidacloprid and its metabolites in environmental and biological samples.
|
| ln Vivo |
In vivo, Imidacloprid-urea is a metabolite formed from the breakdown of imidacloprid. It is not used as a therapeutic agent. Its presence in biological samples can be used as a biomarker of imidacloprid exposure.
|
| Enzyme Assay |
A cell-free assay for Imidacloprid-urea is not applicable as it is not an enzyme inhibitor. Its properties are characterized by standard analytical techniques, such as HPLC and mass spectrometry. It is used as a reference standard in these assays.
|
| Cell Assay |
Cellular experiments with Imidacloprid-urea are not typical, as it is not a pharmacologically active compound. Its primary application is as an analytical standard in environmental and food safety testing.
|
| Animal Protocol |
In vivo animal experiments for Imidacloprid-urea are not applicable, as it is a metabolite and not a therapeutic agent.
|
| ADME/Pharmacokinetics |
Imidacloprid-urea has a molecular formula of C9H10ClN3O and a molecular weight of 211.65 g/mol. Its CAS number is 120868-66-8. The compound is typically supplied as a solution in acetonitrile at a concentration of 100 µg/mL for analytical use. Specific pharmacokinetic properties are not applicable as it is not a therapeutic drug.
|
| Toxicity/Toxicokinetics |
Toxicity data for Imidacloprid-urea are not provided in the available sources. As a pesticide metabolite, it should be handled with appropriate safety precautions. It is intended for research and analytical use only and is not for human consumption.
|
| References | |
| Additional Infomation |
Imidacloprid is an imidazolidinone compound with the structure imidazolidin-2-one substituted at the 1-position with a (6-chloropyridin-3-yl)methyl group. It is a metabolite of the insecticide imidacloprid and functions as an exogenous metabolite in marine environments. It is a monochloropyridine compound, belonging to the imidazolidinone class and also a urea class of compounds.
Imidacloprid-urea (CAS: 120868-66-8) is a metabolite of the neonicotinoid pesticide imidacloprid. Its synonyms include 1-((6-Chloropyridin-3-yl)methyl)imidazolidin-2-one. The compound is used as an analytical standard for the detection of imidacloprid residues. It is not a therapeutic drug and is strictly for research and analytical purposes. |
| Molecular Formula |
C9H10N3OCL
|
|---|---|
| Molecular Weight |
211.6482
|
| Exact Mass |
211.051
|
| CAS # |
120868-66-8
|
| PubChem CID |
15390532
|
| Appearance |
Off-white to light yellow solid powder
|
| Density |
1.359g/cm3
|
| Boiling Point |
478.388ºC at 760 mmHg
|
| Flash Point |
243.12ºC
|
| Vapour Pressure |
0mmHg at 25°C
|
| Index of Refraction |
1.596
|
| LogP |
0.838
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
2
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
14
|
| Complexity |
224
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
ADWTYURAFSWNSU-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C9H10ClN3O/c10-8-2-1-7(5-12-8)6-13-4-3-11-9(13)14/h1-2,5H,3-4,6H2,(H,11,14)
|
| Chemical Name |
1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-one
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~125 mg/mL (~590.60 mM)
H2O : ~12.5 mg/mL (~59.06 mM) |
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.7248 mL | 23.6239 mL | 47.2478 mL | |
| 5 mM | 0.9450 mL | 4.7248 mL | 9.4496 mL | |
| 10 mM | 0.4725 mL | 2.3624 mL | 4.7248 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
