| Size | Price | Stock | Qty |
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| 1mg |
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| 5mg |
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| 100mg | |||
| Other Sizes |
| Targets |
Hosenkoside B's precise molecular target is not fully defined, but as a natural product, it is the subject of research into its potential biological activities. It is generally categorized under "Others" in terms of its target and pathway. Its biological activities, if any, are likely related to its complex glycosidic structure, which is characteristic of many bioactive plant-derived saponins.
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|---|---|
| ln Vitro |
Hosenkoside B has not been widely reported to have specific in vitro activities like enzyme inhibition. As a natural product, it may be studied for various potential properties, but its primary use is as a chemical reference standard or a research compound for isolation and structure-activity studies. Further research is needed to elucidate its specific biological activities.
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| ln Vivo |
Hosenkoside B does not have established in vivo activities as a therapeutic agent. As a natural product from a plant source, it is of interest for phytochemical and pharmacological research, but detailed in vivo efficacy data are lacking. Its effects in a living organism would be dependent on further investigation.
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| Enzyme Assay |
In vitro assays for Hosenkoside B are not standard. If used, the compound would be dissolved in an appropriate solvent, such as DMSO, and tested in various biological assays to screen for potential activities. These could include antioxidant assays (e.g., DPPH radical scavenging), anti-inflammatory assays (e.g., measuring cytokine production in immune cells), or cytotoxicity assays against cancer cell lines.
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| Cell Assay |
Hosenkoside B is not typically used in cell-based assays as a standard pharmacologically active compound. If used, cells would be treated with varying concentrations of the compound, and cell viability, proliferation, or other endpoints would be assessed using standard assays. Its effects, if any, would be determined experimentally.
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| Animal Protocol |
Hosenkoside B is not typically used in animal studies as a therapeutic agent. It is a research chemical used in the laboratory for phytochemical and pharmacological studies. Any in vivo studies would be related to its potential biological activities as a natural product.
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| ADME/Pharmacokinetics |
Hosenkoside B has a molecular weight of 979.15 g/mol and a chemical formula of C48H82O20. It is a large, highly glycosylated molecule with a logP of 0.18. Its oral bioavailability is expected to be very low due to its large size and polarity. It is poorly absorbed and is primarily metabolized by the gut microbiota. The compound is stable for long-term storage as a powder at -20°C for up to 3 years.
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| Toxicity/Toxicokinetics |
Hosenkoside B is generally well-tolerated in research settings. As a natural product, its toxicity profile is not fully characterized. Preclinical studies would involve standard toxicology assessments to determine its safety margin and potential side effects. It is for research use only and is not intended for human therapeutic or diagnostic use.
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| References | |
| Additional Infomation |
Reports indicate that balsam flowers contain Hosenkoside B, and relevant data is available for reference.
Hosenkoside B is a natural baccharane glycoside from Impatiens balsamina L.. It is a complex triterpenoid saponin used as a research tool in natural product chemistry and pharmacology. Its high molecular weight and complex structure make it a compound of interest for studying the bioactivity of plant-derived glycosides. |
| Molecular Formula |
C48H82O20
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|---|---|
| Molecular Weight |
979.1527
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| Exact Mass |
978.539
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| CAS # |
156764-82-8
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| PubChem CID |
124928622
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| Appearance |
White to light yellow solid powder
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| Density |
1.4±0.1 g/cm3
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| Boiling Point |
1075.9±65.0 °C at 760 mmHg
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| Flash Point |
604.5±34.3 °C
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| Vapour Pressure |
0.0±0.6 mmHg at 25°C
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| Index of Refraction |
1.626
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| LogP |
0.18
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| Hydrogen Bond Donor Count |
13
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| Hydrogen Bond Acceptor Count |
20
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| Rotatable Bond Count |
12
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| Heavy Atom Count |
68
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| Complexity |
1700
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| Defined Atom Stereocenter Count |
27
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| SMILES |
C[C@H](CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)[C@H]2CC[C@@]3(CC[C@@]4([C@@H]([C@H]3O)CC[C@H]5[C@]4(CC[C@@H]6[C@@]5(CC[C@@H]([C@@]6(C)CO)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C)C)C)CO2
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| InChi Key |
GBXXXUUAOFPGRP-FLOLCGAJSA-N
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| InChi Code |
InChI=1S/C48H82O20/c1-22(19-62-41-37(59)34(56)31(53)25(16-49)64-41)24-8-13-48(21-63-24)15-14-46(4)23(40(48)61)6-7-29-44(2)11-10-30(45(3,20-52)28(44)9-12-47(29,46)5)67-43-39(36(58)33(55)27(18-51)66-43)68-42-38(60)35(57)32(54)26(17-50)65-42/h22-43,49-61H,6-21H2,1-5H3/t22-,23-,24-,25-,26-,27-,28-,29-,30+,31-,32-,33-,34+,35+,36+,37-,38-,39-,40-,41-,42+,43+,44+,45+,46-,47-,48-/m1/s1
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| Chemical Name |
(2R,3R,4S,5S,6R)-2-[(2R)-2-[(1R,2S,2'R,4aR,4bR,6aR,7R,8S,10aR,10bR,12aS)-8-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-1-hydroxy-7-(hydroxymethyl)-4a,4b,7,10a-tetramethylspiro[3,4,5,6,6a,8,9,10,10b,11,12,12a-dodecahydro-1H-chrysene-2,5'-oxane]-2'-yl]propoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.0213 mL | 5.1065 mL | 10.2129 mL | |
| 5 mM | 0.2043 mL | 1.0213 mL | 2.0426 mL | |
| 10 mM | 0.1021 mL | 0.5106 mL | 1.0213 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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