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    Filastatin
    Filastatin

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V2202
    CAS #: 431996-53-1Purity ≥98%

    Description:Filastatin is a novel and long-lasting inhibitor of Candida albicans filamentation. it is nontoxic to human cells, Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect.

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    Molecular Formula: C18H18ClN3O3
    Exact Mass: 359.1037
    Molecular Weight: 359.81
    Elemental Analysis: C, 60.09; H, 5.04; Cl, 9.85; N, 11.68; O, 13.34

    Chemical Name: (3-Chloro-4-methyl-phenyl)-[4-(4-nitro-phenyl)-piperazin-1-yl]-methanone

    InChi Key: PNECWWUOUHGWQG-UHFFFAOYSA-N

    InChi Code: InChI=1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3

    SMILES Code: O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2


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    These protocols are for reference only. InvivoChem does not independently validate these methods.

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