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| Other Sizes |
| Targets |
Ethyl caprate does not have a specific biological target in the context of drug action. It is not a pharmacologically active compound that binds to receptors or enzymes. Its primary roles are as a metabolite, a flavor component, and a chemical intermediate. In biological systems, it occurs naturally and is metabolized by esterases to decanoic acid and ethanol. It does not exert its effects through defined molecular targets, and its activity is purely physical and chemical, such as its emollient and solvent properties.
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| ln Vitro |
Ethyl decanoate is a biochemical reagent that can be utilized in life science research as an organic compound or biological material.
In vitro, Ethyl caprate is primarily used as a reference standard in analytical chemistry (e.g., GC-MS, HPLC) for flavor and fermentation studies. It is not used as an active compound in cellular assays to study signaling pathways because it lacks pharmacological activity. It may serve as a substrate in studies of esterase activity or lipid metabolism, but its main in vitro applications are in analytical method development and quality control of flavors and fragrances. |
| ln Vivo |
In vivo, Ethyl caprate is not used as a drug. It is a naturally occurring compound found in foods and beverages and is generally recognized as safe (GRAS) as a flavoring agent. When ingested, it is hydrolyzed to decanoic acid and ethanol, which are metabolized via normal pathways. It has no known therapeutic applications. Its use is limited to its physical properties as a flavorant and emollient, and it is not administered therapeutically in animal models.
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| Enzyme Assay |
The in vitro assay for Ethyl caprate typically involves analytical techniques for identification and quantification, such as gas chromatography-mass spectrometry (GC-MS) or high-performance liquid chromatography (HPLC). Purity and composition are assessed using these methods, with physical properties like refractive index (1.4256) and density (0.8650) also measured for characterization. There is no enzyme or receptor binding assay because the compound has no defined biological target. Protocols follow standard analytical chemistry procedures.
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| Cell Assay |
In vitro cellular assays are not performed with Ethyl caprate, as it is not a biologically active compound used to study cell signaling, proliferation, or toxicity. It is not considered a pharmacological agent; therefore, standard cell viability assays (MTT, CCK-8), apoptosis assays, or receptor activation studies are not applicable. Its interactions are physical (solvent, emollient) rather than biological, and it is generally regarded as inert in cell culture systems.
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| Animal Protocol |
In vivo animal studies are not conducted for Ethyl caprate as a therapeutic candidate. It is not a drug and has no known therapeutic applications. Its use in animals would be limited to being a dietary component or a standard in nutritional or metabolic studies. Since it is a common food additive, it is considered safe, and there is no pharmacological profile that warrants animal efficacy or safety studies for drug development.
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| ADME/Pharmacokinetics |
Ethyl caprate is a small, lipophilic molecule with a molecular weight of 200.32, a LogP of 4.96, and a density of 0.9±0.1 g/cm³. It is practically insoluble in water but soluble in ethanol and ether. If absorbed, it is metabolized by esterases to decanoic acid and ethanol, which enter normal metabolic pathways. It should be stored as a powder at -20°C (up to 3 years) or in solvent at -80°C (up to 6 months). It is typically shipped at room temperature.
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| Toxicity/Toxicokinetics |
Ethyl caprate is generally considered safe for its intended uses as a flavoring agent and food additive. It is not known to be acutely toxic. Skin or eye contact may cause mild irritation; ingestion of large amounts could cause gastrointestinal discomfort. It is not intended for human therapeutic use and is strictly for research purposes. For detailed toxicity information, consult the safety data sheet.
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| Additional Infomation |
Ethyl decanoate is an ethyl fatty acid ester of decanoic acid and is a metabolite. It is both an ethyl fatty acid ester and a decanoate ester. Ethyl decanoate has been reported in Mandragora autumnalis, Echinophora tenuifolia, and other organisms with relevant data. Ethyl decanoate is a metabolite found in or produced by Saccharomyces cerevisiae.
Ethyl caprate (ethyl decanoate) is a fatty acid ethyl ester with CAS 110-38-3, molecular formula C12H24O2, and MW 200.32. It is a colorless to light yellow liquid with a sweet, fruity odor. It is widely used as a flavor and food additive, naturally occurring in fruits and fermentation products. It serves as a research reagent in analytical chemistry and is not a drug. It is not FDA-approved and is for research only. |
| Molecular Formula |
C12H24O2
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|---|---|
| Molecular Weight |
200.32
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| Exact Mass |
200.177
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| CAS # |
110-38-3
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| PubChem CID |
8048
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| Appearance |
Colorless to light yellow liquid
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| Density |
0.9±0.1 g/cm3
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| Boiling Point |
242.5±3.0 °C at 760 mmHg
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| Melting Point |
-20°C
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| Flash Point |
102.2±0.0 °C
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| Vapour Pressure |
0.0±0.5 mmHg at 25°C
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| Index of Refraction |
1.430
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| LogP |
4.96
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
10
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| Heavy Atom Count |
14
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| Complexity |
132
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| Defined Atom Stereocenter Count |
0
|
| SMILES |
O(C([H])([H])C([H])([H])[H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O
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| InChi Key |
RGXWDWUGBIJHDO-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C12H24O2/c1-3-5-6-7-8-9-10-11-12(13)14-4-2/h3-11H2,1-2H3
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| Chemical Name |
ethyl decanoate
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| Synonyms |
Capric acid ethyl ester; Ethyl decanoate; Ethyl caprate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.9920 mL | 24.9601 mL | 49.9201 mL | |
| 5 mM | 0.9984 mL | 4.9920 mL | 9.9840 mL | |
| 10 mM | 0.4992 mL | 2.4960 mL | 4.9920 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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