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    Ethisterone
    Ethisterone

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V1743
    CAS #: 434-03-7Purity ≥98%

    Description: Ethisterone (Aethisteron; Progestoral; NSC-9565; NSC9565) is a progestogen hormone and a synthetic contraceptive that is being developed as an anticancer agent for the treatment of prostate cancer. It is the first orally bioactive progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone or 19-norandrostane), the 17α-ethynyl analog of testosterone. Ethisterone is a progestogen that counteracts estrogenic proliferative effects on the endometrium. Ethisterone (dose range: 40 μg-5 mg/day × 6) stimulates weight gain but has a rather weak effect on the sulphate pools and incorporation rates in mice.

    References: Acta Pharmacol Toxicol (Copenh). 1971;29(23):177-93.

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    • 香港大学
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    Molecular Weight (MW)312.45 
    FormulaC21H28O2 
    CAS No.434-03-7 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: <1 mg/mL
    Water: <1 mg/mL
    Ethanol: <1 mg/mL
    Other info

    Chemical Name: (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

    InChi Key: CHNXZKVNWQUJIB-CEGNMAFCSA-N

    InChi Code: InChI=1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

    SMILES Code: O=C1CC[[email protected]]2(C)[[email protected]@]3([H])CC[[email protected]]4(C)[[email protected]@](C#C)(O)CC[[email protected]@]4([H])[[email protected]]3([H])CCC2=C1           

    Synonyms

    NSC 9565; Aethisteron; Progestoral; NSC-9565; NSC9565; Ethisterone


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