| Size | Price | Stock | Qty |
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| 250mg |
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| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
Dansylamide is a fluorescent dye that does not have a specific biological target. Its mechanism of action involves fluorescence upon excitation, allowing it to be used as a probe for labeling and detecting biomolecules. The dansyl group is fluorescent and can be excited at specific wavelengths to emit detectable signals. Dansylamide is used to label substances with the fluorescent dansyl group for detection in biochemical assays.
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| ln Vitro |
In vitro, dansylamide is used as a fluorescent dye for labeling and detecting biomolecules. It is a reactive fluorescent dye used in biochemistry and chemistry to label substances with the fluorescent dansyl group. The compound is used in biochemical experiments for labeling dansyl groups. Dansylamide is used as a fluorescent probe for the detection and quantification of various analytes. Its fluorescence properties make it valuable for a wide range of analytical applications.
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| ln Vivo |
In vivo, dansylamide is not used as a therapeutic agent. It is a fluorescent dye used in research applications for labeling and detecting biomolecules. The compound is not administered to animals or humans for therapeutic purposes. It is for research use only and is not intended for human or veterinary use.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays are not typically performed for dansylamide, as it is a fluorescent dye rather than a pharmacologically active agent. Its fluorescence properties can be characterized using spectrofluorometry. The compound's ability to label biomolecules is assessed by measuring fluorescence intensity after conjugation. These assays confirm the compound's utility as a fluorescent probe.
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| Cell Assay |
In vitro cell-based assays for dansylamide are not typically performed, as the compound is a fluorescent dye rather than a pharmacologically active agent. However, it can be used to label cellular components for imaging applications. Cells are treated with dansylamide or dansylamide-conjugated probes, and fluorescence is detected by microscopy or flow cytometry. These assays confirm the compound's utility as a fluorescent probe for cell imaging.
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| Animal Protocol |
In vivo animal experiments for dansylamide are not typically conducted, as the compound is a fluorescent dye rather than a therapeutic agent. It is not administered to animals for pharmacological purposes. The compound is for research use only and is not intended for human or veterinary use.
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| ADME/Pharmacokinetics |
Pharmacokinetic (PK) data for dansylamide are not relevant, as the compound is a fluorescent dye rather than a therapeutic agent. It has a molecular weight of 250.32 g/mol and a molecular formula of C₁₂H₁₄N₂O₂S. It is a solid powder. The compound is for research use only and is not administered as a therapeutic agent.
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| Toxicity/Toxicokinetics |
The toxicity profile of dansylamide has not been extensively characterized. As a research chemical, it should be handled with appropriate safety precautions. The compound is for research use only and is not intended for human or veterinary use. Standard safety precautions for handling chemical compounds should be followed.
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| References | |
| Additional Infomation |
Dansylamide is a reactive fluorescent dye used in biochemistry and chemistry to label substances with the fluorescent dansyl group. It has a molecular formula of C₁₂H₁₄N₂O₂S and a molecular weight of 250.32 g/mol. Dansylamide is used as a fluorescent probe for the detection and quantification of various analytes. It is a research tool and has no clinical applications.
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| Molecular Formula |
C12H14N2O2S
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|---|---|
| Molecular Weight |
250.3168
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| Exact Mass |
250.077
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| CAS # |
1431-39-6
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| PubChem CID |
65077
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| Appearance |
White to off-white solid powder
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| Density |
1.3±0.1 g/cm3
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| Boiling Point |
435.4±37.0 °C at 760 mmHg
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| Melting Point |
218-221ºC
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| Flash Point |
217.1±26.5 °C
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| Vapour Pressure |
0.0±1.0 mmHg at 25°C
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| Index of Refraction |
1.655
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| LogP |
2.01
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
17
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| Complexity |
361
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
TYNBFJJKZPTRKS-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)
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| Chemical Name |
5-(dimethylamino)naphthalene-1-sulfonamide
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~150 mg/mL (~599.23 mM)
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.9949 mL | 19.9744 mL | 39.9489 mL | |
| 5 mM | 0.7990 mL | 3.9949 mL | 7.9898 mL | |
| 10 mM | 0.3995 mL | 1.9974 mL | 3.9949 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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