| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
| Targets |
The molecular target of CV 11464 is not well-characterized in publicly available literature. It is a sulfated ascorbate derivative that may modulate oxidative stress and cellular signaling. Further investigation is needed to identify its specific molecular targets and mechanism of action.
|
|---|---|
| ln Vitro |
Detailed in vitro activity data for CV 11464 are not available in public literature. The compound is listed as a bioactive chemical, but specific IC50 values, selectivity profiles, and functional assay results have not been reported. Comprehensive in vitro characterization remains to be performed.
|
| ln Vivo |
In vivo activity data for CV 11464 are not available in public literature. The compound has been catalogued for research use, but no animal model efficacy studies or pharmacokinetic data have been reported. Further preclinical evaluation is required to assess its therapeutic potential.
|
| Enzyme Assay |
No published protocols for enzyme or receptor binding assays with CV 11464 are available in public literature. Standard biochemical assay protocols would need to be developed based on the compound's chemical structure and predicted biological activity once its molecular targets are identified.
|
| Cell Assay |
No published protocols for cell-based assays with CV 11464 are available in public literature. Standard cell culture and functional assay protocols would need to be developed to evaluate its cellular activity, cytotoxicity, and mechanism of action.
|
| Animal Protocol |
No published protocols for in vivo animal studies with CV 11464 are available in public literature. Standard preclinical evaluation protocols including pharmacokinetic studies, dose-ranging efficacy studies, and safety assessments would need to be developed.
|
| Molecular Formula |
C24H44O12S2.2NA
|
|---|---|
| Molecular Weight |
632.6926
|
| Exact Mass |
632.191
|
| CAS # |
144315-07-1
|
| PubChem CID |
54699172
|
| Appearance |
Typically exists as solid at room temperature
|
| tPSA |
205
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
12
|
| Rotatable Bond Count |
22
|
| Heavy Atom Count |
40
|
| Complexity |
877
|
| Defined Atom Stereocenter Count |
2
|
| SMILES |
CCCCCCCCCCCCCCCCCCOC1=C([C@H](OC1=O)[C@H](COS(=O)(=O)[O-])OS(=O)(=O)[O-])O.[Na+].[Na+]
|
| InChi Key |
UOKAGUREYTVUIN-ULXOMSGMSA-L
|
| InChi Code |
InChI=1S/C24H44O12S2.2Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-33-23-21(25)22(35-24(23)26)20(36-38(30,31)32)19-34-37(27,28)29;;/h20,22,25H,2-19H2,1H3,(H,27,28,29)(H,30,31,32);;/q;2*+1/p-2/t20-,22+;;/m0../s1
|
| Chemical Name |
disodium;[(1S)-1-[(2R)-3-hydroxy-4-octadecoxy-5-oxo-2H-furan-2-yl]-2-sulfonatooxyethyl] sulfate
|
| Synonyms |
CV11464; CV-11464; CV 11464
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.5806 mL | 7.9028 mL | 15.8055 mL | |
| 5 mM | 0.3161 mL | 1.5806 mL | 3.1611 mL | |
| 10 mM | 0.1581 mL | 0.7903 mL | 1.5806 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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