| Size | Price | Stock | Qty |
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| 10mg |
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| 100mg | |||
| Other Sizes |
| ln Vitro |
No in vitro pharmacological activity data (such as enzyme inhibition, cell viability, or signaling pathway modulation) are available for cholesteryl behenate in the provided search results. The available information focuses on its role as a chemical standard and a structural lipid component, rather than its biological activity in cell-based assays.
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|---|---|
| ln Vivo |
No in vivo pharmacological or efficacy data are available for cholesteryl behenate in the provided search results. The compound is not described as having therapeutic effects in animal models; its primary role in biological contexts is as a structural lipid component of lipoproteins.
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| ADME/Pharmacokinetics |
No pharmacokinetic data (including absorption, distribution, metabolism, excretion, half-life, or oral bioavailability) are available for cholesteryl behenate as a pure compound in the provided search results. Biochemically, cholesterol esters like cholesteryl behenate are known to be taken up by cells via receptor-mediated endocytosis of LDL particles and are subsequently hydrolyzed within lysosomes by acid cholesteryl ester hydrolase to release free cholesterol. However, this describes the general metabolic fate of cholesteryl esters in the body rather than specific pharmacokinetic parameters for the pure compound.
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| Toxicity/Toxicokinetics |
Based on available safety data, cholesteryl behenate is classified as a non-hazardous substance. It is not listed as a carcinogen by NTP, IARC, OSHA, or ACGIH, and contains no chemicals known to the State of California to cause cancer, birth defects, or reproductive harm under Proposition 65. The compound does not require GHS hazard labeling and is not subject to SARA reporting requirements. During combustion, it may emit irritant fumes, and incompatible materials include strong acids/alkalis and strong oxidizing/reducing agents. Standard handling precautions include avoiding inhalation and contact with eyes and skin, using appropriate personal protective equipment, and ensuring adequate ventilation. The toxicological effects of this product have not been thoroughly studied. The compound is stable under recommended storage conditions (powder at -20°C for up to 3 years or 4°C for 2 years; in solvent at -80°C for 6 months or -20°C for 1 month).
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| References | |
| Additional Infomation |
Behenicol ester is a cholesterol ester formed by the condensation of cholesterol and behenic acid. It plays a metabolic role in mice, and its function is related to docosanoic acid.
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| Molecular Formula |
C49H88O2
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|---|---|
| Molecular Weight |
709.22182
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| Exact Mass |
708.678
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| CAS # |
61510-09-6
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| Related CAS # |
Cholesterol myristate;1989-52-2
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| PubChem CID |
16061339
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| Appearance |
White to off-white solid powder
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| Density |
0.9±0.1 g/cm3
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| Boiling Point |
711.0±39.0 °C at 760 mmHg
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| Flash Point |
385.1±14.6 °C
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| Vapour Pressure |
0.0±2.3 mmHg at 25°C
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| Index of Refraction |
1.504
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| LogP |
21.33
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
27
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| Heavy Atom Count |
51
|
| Complexity |
996
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| Defined Atom Stereocenter Count |
8
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| SMILES |
CCCCCCCCCCCCCCCCCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C
|
| InChi Key |
WBOQXYUYHINMOC-FTAWAYKBSA-N
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| InChi Code |
InChI=1S/C49H88O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-29-47(50)51-42-34-36-48(5)41(38-42)30-31-43-45-33-32-44(40(4)28-26-27-39(2)3)49(45,6)37-35-46(43)48/h30,39-40,42-46H,7-29,31-38H2,1-6H3/t40-,42+,43+,44-,45+,46+,48+,49-/m1/s1
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| Chemical Name |
[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] docosanoate
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| Synonyms |
Cholesteryl behenate; 61510-09-6; Cholesteryl docosanoate; Cholesterol, docosanoate; 22:0 Cholesteryl ester; .
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
Ethanol : ~2 mg/mL (~2.82 mM)
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.4100 mL | 7.0500 mL | 14.1000 mL | |
| 5 mM | 0.2820 mL | 1.4100 mL | 2.8200 mL | |
| 10 mM | 0.1410 mL | 0.7050 mL | 1.4100 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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