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    Cethromycin
    Cethromycin

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V4412
    CAS #: 205110-48-1 Purity ≥98%

    Description: Cethromycin (also known as ABT-773, Abbott-195773, A-195773) is a ketolide antibiotic with a similar mechanism of action to telithromycin with an apparently better safety profile. Cethromycin displays in vitro activity against selected gram-positive, gram-negative, and atypical bacteria. The proposed indication of cethromycin is treatment of mild to moderate community-acquired bacterial pneumonia in patients. Cethromycin has an orphan drug designation for tularemia, plague, and anthrax prophylaxis. Preliminary data on adverse effects suggest that cethromycin is safe and gastrointestinal adverse effects appear to be dose-related.

    References:  2012 Apr;56(4):2037-47.


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    Cethromycin

    Name: Cethromycin
    CAS#: 205110-48-1
    Chemical Formula: C42H59N3O10
    Exact Mass: 765.42
    Molecular Weight: 765.945
    Elemental Analysis: C, 65.86; H, 7.76; N, 5.49; O, 20.89
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: Cethromycin; ABT-773; ABT 773; ABT773; A-195773; A 195773; A195773; Abbott-195773; Abbott195773; Abbott 195773
    IUPAC/Chemical Name: (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-ethyl-3a,7,9,11,13,15-hexamethyl-11-(((E)-3-(quinolin-3-yl)allyl)oxy)octahydro-2H-[1]oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetraone
    InChi Key: PENDGIOBPJLVBT-ONLVEXIXSA-N
    InChi Code: InChI=1S/C42H59N3O10/c1-11-32-42(8)36(44-40(50)55-42)25(4)33(46)23(2)21-41(7,51-18-14-15-28-20-29-16-12-13-17-30(29)43-22-28)37(26(5)34(47)27(6)38(49)53-32)54-39-35(48)31(45(9)10)19-24(3)52-39/h12-17,20,22-27,31-32,35-37,39,48H,11,18-19,21H2,1-10H3,(H,44,50)/b15-14+/t23-,24-,25+,26+,27-,31+,32-,35-,36-,37-,39+,41-,42-/m1/s1
    SMILES Code: CC[[email protected]]1OC([[email protected]@H](C([[email protected]@H]([[email protected]]([[email protected]@](C[[email protected]](C([[email protected]@H]([[email protected]]2NC(O[[email protected]]12C)=O)C)=O)C)(OC/C=C/C3=CN=C(C=CC=C4)C4=C3)C)O[[email protected]@H]5O[[email protected]@H](C[[email protected]](N(C)C)[[email protected]]5O)C)C)=O)C)=O


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