| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
Carbostyril 124 does not have a specific biological target as it is a chromophore and laser dye. Its function is to absorb light and emit fluorescence, which can be used for sensitization and optical detection. As an antenna molecule, it facilitates light absorption and enhances fluorescence efficiency. The compound is used as a building block in the synthesis of luminescent lanthanide complexes. Its chromophore properties make it useful for various optical and imaging applications.
|
|---|---|
| ln Vitro |
In aqueous solutions, the distinctive metallic fluorescence of europium and terbium complexes is detected upon activation of the cs124 chromophore at 320 nm [1].
In vitro, Carbostyril 124 is used as a chromophore and laser dye. The compound acts as an antenna molecule that facilitates light absorption and enhances fluorescence efficiency. It has been used as a building block in the synthesis of luminescent lanthanide complexes. The characteristic metal-based luminescence was observed for europium and terbium complexes in aqueous solution following excitation of the CS124 chromophore at 320 nm. Carbostyril 124 is suitable as a laser dye. |
| ln Vivo |
Carbostyril 124 is not used as a therapeutic agent and has no established in vivo pharmacological activity. Its primary application is as a research tool for optical detection and as a building block for luminescent complexes. The compound is used in the synthesis of luminescent lanthanide complexes for various applications. It is not administered to animals for therapeutic purposes.
|
| Enzyme Assay |
In vitro experiments with Carbostyril 124 typically involve its use as a chromophore or laser dye. The compound is dissolved in appropriate solvents (e.g., ethanol, methanol, DMSO) and its fluorescence properties are measured using a spectrophotometer or fluorometer. The compound exhibits characteristic fluorescence upon excitation at approximately 320 nm. For the synthesis of luminescent complexes, Carbostyril 124 is used as a building block and reacted with lanthanide salts to form coordination complexes. The resulting complexes exhibit characteristic metal-based luminescence.
|
| Cell Assay |
Carbostyril 124 is not typically used in cell-based assays as it is primarily a chromophore for optical applications. However, it could be used in cell-based imaging applications if conjugated to targeting molecules. The compound's fluorescence properties would allow for the visualization of labeled cellular structures. The compound is typically dissolved in DMSO or ethanol for preparation of stock solutions.
|
| Animal Protocol |
Specific in vivo animal experiment protocols for Carbostyril 124 are not detailed in the available literature. The compound is primarily used as a chromophore for in vitro optical applications. For potential in vivo imaging applications, the compound would need to be conjugated to targeting molecules and formulated for administration.
|
| ADME/Pharmacokinetics |
Carbostyril 124 has a molecular weight of 174.20 g/mol and the formula C10H10N2O. The compound is also known as 7-amino-4-methyl-2(1H)-quinolinone and 7-amino-4-methyl-carbostyril. For storage, the compound is kept at room temperature, protected from light. It is a chromophore that can be used as a laser dye for sensitization and optical detection. The compound acts as an antenna molecule that facilitates light absorption and enhances fluorescence efficiency. It has been used as a building block in the synthesis of luminescent lanthanide complexes.
|
| Toxicity/Toxicokinetics |
Specific toxicological data for Carbostyril 124 are not provided in the available sources. As a research chemical, it is intended for laboratory use only and is not for human or veterinary use. Standard laboratory safety precautions should be followed when handling this compound, including the use of gloves and eye protection. The compound may cause irritation to skin, eyes, and respiratory tract upon contact.
|
| References |
|
| Additional Infomation |
Carbostyril 124 (CAS 19840-99-4) is a chromophore that can be used as a laser dye for sensitization and optical detection. It has the molecular formula C10H10N2O and a molecular weight of 174.20 g/mol. The compound is also known as 7-amino-4-methyl-2(1H)-quinolinone and 7-amino-4-methyl-carbostyril. Carbostyril 124 acts as an antenna molecule that facilitates light absorption and enhances fluorescence efficiency. It has been used as a building block in the synthesis of luminescent lanthanide complexes. The compound is suitable as a laser dye. It is intended for research use only.
|
| Molecular Formula |
C10H10N2O
|
|---|---|
| Molecular Weight |
174.1992
|
| Exact Mass |
174.079
|
| CAS # |
19840-99-4
|
| PubChem CID |
88277
|
| Appearance |
Yellow to brown solid powder
|
| Density |
1.2±0.1 g/cm3
|
| Boiling Point |
417.6±45.0 °C at 760 mmHg
|
| Melting Point |
>275ºC (dec.)
|
| Flash Point |
206.4±28.7 °C
|
| Vapour Pressure |
0.0±1.0 mmHg at 25°C
|
| Index of Refraction |
1.627
|
| LogP |
0.71
|
| Hydrogen Bond Donor Count |
2
|
| Hydrogen Bond Acceptor Count |
2
|
| Rotatable Bond Count |
0
|
| Heavy Atom Count |
13
|
| Complexity |
260
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
MJXYFLJHTUSJGU-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C10H10N2O/c1-6-4-10(13)12-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3,(H,12,13)
|
| Chemical Name |
7-amino-4-methyl-1H-quinolin-2-one
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.7405 mL | 28.7026 mL | 57.4053 mL | |
| 5 mM | 1.1481 mL | 5.7405 mL | 11.4811 mL | |
| 10 mM | 0.5741 mL | 2.8703 mL | 5.7405 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
