| Size | Price | Stock | Qty |
|---|---|---|---|
| 50mg |
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| 100mg |
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| 250mg | |||
| Other Sizes |
| Targets |
Anilofos does not have a specific pharmacological target, as it is a herbicide. Its herbicidal activity is related to its organophosphorus chemistry, which interferes with plant metabolic processes. It is absorbed by roots and translocated to shoots or leaves, where it inhibits plant growth.
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|---|---|
| ln Vitro |
Anilofos is not a pharmacologically active compound, so it does not have defined in vitro pharmacological activity. Its effects are studied in the context of herbicide activity and toxicology. In vitro studies may assess its cytotoxicity or its effects on cellular processes, but these are not pharmacological activities.
|
| ln Vivo |
Anilofos is not used in vivo as a pharmacological agent. Its use is limited to agricultural applications as a herbicide. It is not administered to animals or humans for therapeutic purposes.
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| Enzyme Assay |
Anilofos does not have a pharmacological receptor binding assay. Its interactions are studied in the context of environmental toxicology and herbicide activity. Analytical methods are used to detect and quantify the compound in environmental samples.
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| Cell Assay |
Anilofos is not used in cellular assays for pharmacological purposes. Its effects on cells may be studied in toxicological research to assess its cytotoxicity and potential health effects. However, these are not pharmacological assays.
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| Animal Protocol |
Anilofos is not used in animal studies for pharmacological purposes. Its effects on animals are studied in the context of toxicology and environmental health. It is not administered as a therapeutic agent.
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| ADME/Pharmacokinetics |
Anilofos is not a drug and does not have pharmacokinetic properties in the context of pharmacology. Its environmental fate and transport are studied in the context of herbicide use. It is not intended for systemic administration.
|
| Toxicity/Toxicokinetics |
Anilofos is moderately toxic to mammals. It is an organophosphorus compound, and exposure can cause toxicity. It is a skin and eye irritant. Its use is regulated as a pesticide. It is not safe for human consumption or therapeutic use.
|
| References | |
| Additional Infomation |
Anilolphos is an aniline compound.
Anilofos is a pre-emergence and early post-emergence selective organophosphorus herbicide used for weed control in rice. It is moderately toxic to mammals. It is not a pharmaceutical agent and has no therapeutic applications. It is a pesticide. |
| Molecular Formula |
C13H19CLNO3PS2
|
|---|---|
| Molecular Weight |
367.84
|
| Exact Mass |
367.023
|
| CAS # |
64249-01-0
|
| PubChem CID |
91687
|
| Appearance |
White to off-white solid powder
|
| Density |
1.322 g/cm3
|
| Boiling Point |
443.6ºC at 760 mmHg
|
| Melting Point |
50-51ºC
|
| Flash Point |
>100 °C
|
| Index of Refraction |
1.561 (24ºC)
|
| LogP |
4.982
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
5
|
| Rotatable Bond Count |
7
|
| Heavy Atom Count |
21
|
| Complexity |
382
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
NXQDBZGWYSEGFL-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C13H19ClNO3PS2/c1-10(2)15(12-7-5-11(14)6-8-12)13(16)9-21-19(20,17-3)18-4/h5-8,10H,9H2,1-4H3
|
| Chemical Name |
N-(4-chlorophenyl)-2-dimethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~125 mg/mL (~339.81 mM)
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7186 mL | 13.5929 mL | 27.1857 mL | |
| 5 mM | 0.5437 mL | 2.7186 mL | 5.4371 mL | |
| 10 mM | 0.2719 mL | 1.3593 mL | 2.7186 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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