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      Amfebutamone HCl
      Amfebutamone HCl

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      This product is for research use only, not for human use. We do not sell to patients.
      Number： - + Pieces（InventoryPieces）
      InvivoChem Cat #: V1250
      CAS #: 31677-93-7Purity ≥98%

      Description: Amfebutamone HCl (Bupropion, Wellbutrin, Zyban; BW-323; NSC315851; NSC-315851), the hydrochloride salt of Amfebutamone, is a potent and selective norepinephrine-dopamine reuptake inhibitor used as an antidepressant and for smoking cessation. It inhibits the reuptake of dopamine and norepinephrine with IC50s of 6.5 and 3.4 μM, respectively. Amfebutamone is one of the most frequently prescribed antidepressants in the United States.

      References: J Pharmacol Exp Ther. 1999 Jan;288(1):88-92.

      Related CAS #: 31677-93-7 (HCl)   34841-39-9 (free base)  

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      Molecular Weight (MW)276.2
      FormulaC13H18ClNO.HCl
      CAS No.31677-93-7
      Storage-20℃ for 3 years in powder form
      -80℃ for 2 years in solvent
      Solubility (In vitro)DMSO: 8 mg/mL (28.96 mM)
      Water: <1 mg/mL
      Ethanol: <1 mg/mL
      Other info

      Chemical Name: 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride

      InChi Key: HEYVINCGKDONRU-UHFFFAOYSA-N

      InChi Code: InChI=1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H

      SMILES Code: CC(NC(C)(C)C)C(C1=CC=CC(Cl)=C1)=O.[H]Cl

      Synonyms

      NSC-315851; Bupropion, Wellbutrin, Zyban; BW 323; NSC315851; NSC 315851; BW-323; BW323. 


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