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    Amfebutamone HCl
    Amfebutamone HCl

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V1250
    CAS #: 31677-93-7Purity ≥98%

    Description: Amfebutamone HCl (Bupropion, Wellbutrin, Zyban; BW-323; NSC315851; NSC-315851), the hydrochloride salt of Amfebutamone, is a potent and selective norepinephrine-dopamine reuptake inhibitor used as an antidepressant and for smoking cessation. It inhibits the reuptake of dopamine and norepinephrine with IC50s of 6.5 and 3.4 μM, respectively. Amfebutamone is one of the most frequently prescribed antidepressants in the United States.

    References: J Pharmacol Exp Ther. 1999 Jan;288(1):88-92.

    Related CAS #: 31677-93-7 (HCl)   34841-39-9 (free base)  

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    Molecular Weight (MW)276.2
    FormulaC13H18ClNO.HCl
    CAS No.31677-93-7
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 8 mg/mL (28.96 mM)
    Water: <1 mg/mL
    Ethanol: <1 mg/mL
    Other info

    Chemical Name: 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride

    InChi Key: HEYVINCGKDONRU-UHFFFAOYSA-N

    InChi Code: InChI=1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H

    SMILES Code: CC(NC(C)(C)C)C(C1=CC=CC(Cl)=C1)=O.[H]Cl

    Synonyms

    NSC-315851; Bupropion, Wellbutrin, Zyban; BW 323; NSC315851; NSC 315851; BW-323; BW323. 


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