| Size | Price | Stock | Qty |
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| 10mg |
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| 25mg |
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| 50mg |
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| 500mg | |||
| 1g | |||
| Other Sizes |
| Targets |
The precise molecular target of WAY-300716 has not been fully characterized in the available literature. It is described as a useful chemical reagent with antimicrobial, insecticidal, and acaricidal activities. The compound is used in research to study these biological activities. Further studies would be required to identify its specific molecular targets and mechanism of action.
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|---|---|
| ln Vitro |
WAY-300716 exhibits antimicrobial, insecticidal, and acaricidal activities in laboratory studies. It is used as a chemical reagent for research into these biological effects. Specific potency values and detailed activity profiles have not been extensively reported in the available literature. The compound's activity makes it a useful tool for studying antimicrobial and pesticidal mechanisms.
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| ln Vivo |
In vivo activity of WAY-300716 has not been reported in the available literature. The compound is used as a chemical reagent for laboratory research and is not intended for in vivo studies as a drug candidate. Its utility lies in its role as a research tool for antimicrobial and pesticidal studies.
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| Enzyme Assay |
WAY-300716 is used in antimicrobial susceptibility testing to evaluate its activity against various microorganisms. Standard protocols involve broth microdilution or agar diffusion methods to determine minimum inhibitory concentrations (MICs). Insecticidal and acaricidal activities are assessed using appropriate bioassays with target insects or acarids. The compound is tested at varying concentrations, and activity is determined by measuring mortality or growth inhibition.
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| Cell Assay |
Cellular activity of WAY-300716 is evaluated in microbial cultures or insect cell lines. Microorganisms are cultured in appropriate media and exposed to varying concentrations of the compound. Growth inhibition is monitored by optical density measurement or colony counting. For insecticidal studies, target insects are exposed to the compound and mortality is recorded. Specific protocols depend on the organism being studied.
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| Animal Protocol |
In vivo studies are not typically performed with WAY-300716 as it is a chemical reagent for laboratory research. The compound is for research use only and not for therapeutic use. Its primary application is in laboratory research settings for antimicrobial and pesticidal studies.
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| ADME/Pharmacokinetics |
WAY-300716 has a molecular formula of C16H14ClNO and a molecular weight of 271.74. It is typically stored at -20°C. The compound is available as a powder or in solution (10 mM in DMSO). It is a useful chemical reagent for laboratory research. Its physicochemical properties support its use in various research applications.
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| Toxicity/Toxicokinetics |
Toxicological data for WAY-300716 are limited, as the compound is a chemical reagent for research use. It is not intended for human or therapeutic use. Standard laboratory safety precautions should be followed when handling the compound. Comprehensive toxicology profiling is not applicable as the compound is not a drug candidate.
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| Additional Infomation |
WAY-300716 is a useful chemical reagent for laboratory research. It is also known as (4-chlorophenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone. The compound exhibits antimicrobial, insecticidal, and acaricidal activities. It is used in research applications related to these biological activities. The compound's 3,4-dihydroisoquinolinyl structure contributes to its biological properties.
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| Molecular Formula |
C16H14CLNO
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|---|---|
| Molecular Weight |
271.744
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| Exact Mass |
271.076
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| Elemental Analysis |
C, 70.72; H, 5.19; Cl, 13.05; N, 5.15; O, 5.89
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| CAS # |
223735-93-1
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| PubChem CID |
668827
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.256±0.06 g/cm3(Predicted)
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| Boiling Point |
448.2±45.0 °C(Predicted)
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| Flash Point |
224.8±28.7 °C
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| Vapour Pressure |
0.0±1.1 mmHg at 25°C
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| Index of Refraction |
1.626
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| LogP |
3.09
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
19
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| Complexity |
325
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| Defined Atom Stereocenter Count |
0
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| SMILES |
ClC1=CC=C(C(N2CCC3=CC=CC=C3C2)=O)C=C1
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| InChi Key |
AFLIBHSYRRBBBP-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C16H14ClNO/c17-15-7-5-13(6-8-15)16(19)18-10-9-12-3-1-2-4-14(12)11-18/h1-8H,9-11H2
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| Chemical Name |
(4-Chlorophenyl)(3,4-dihydro-2(1H)-isoquinolinyl)methanone
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| Synonyms |
WAY-300716; WAY 300716; WAY300716
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.6800 mL | 18.3999 mL | 36.7999 mL | |
| 5 mM | 0.7360 mL | 3.6800 mL | 7.3600 mL | |
| 10 mM | 0.3680 mL | 1.8400 mL | 3.6800 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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