| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
Purity: ≥98%
| Targets |
As a chemical reagent, 3,3'-Dimethylbiphenyl does not have a specific biological target. Its utility is in organic synthesis, where it acts as a building block for more complex molecules. It is used in palladium-catalyzed coupling reactions to form carbon-carbon bonds.
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|---|---|
| ln Vitro |
In vitro, 3,3'-Dimethylbiphenyl is used as a reagent for chemical synthesis, not as a drug. Its activity is measured by its efficiency in coupling reactions, typically assessed by the yield and purity of the desired product. It is a valuable tool in medicinal chemistry for creating complex molecules.
|
| ln Vivo |
As a chemical reagent, 3,3'-Dimethylbiphenyl is not used for in vivo applications. Its role is strictly as a synthetic intermediate in the laboratory. It is not administered to living organisms for therapeutic or research purposes.
|
| Enzyme Assay |
There is no biological assay for this compound. Its performance is evaluated in chemical synthesis protocols. The reaction progress is monitored using thin-layer chromatography (TLC) or high-performance liquid chromatography (HPLC), and the product is characterized by NMR and mass spectrometry to confirm successful coupling.
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| Cell Assay |
Cellular experiments are not applicable to this chemical reagent. It is used in test tubes for organic synthesis, not in cell culture. Its role is to create compounds that may later be tested in cells, but the reagent itself is not used in cellular assays.
|
| Animal Protocol |
In vivo animal experiments are not applicable to this compound. It is a chemical reagent used exclusively for in vitro synthesis. It is not administered to animals or used in any biological model system.
|
| Molecular Formula |
C14H14
|
|---|---|
| Molecular Weight |
182.26096
|
| Exact Mass |
182.109
|
| CAS # |
612-75-9
|
| Related CAS # |
612-75-9;
|
| PubChem CID |
11931
|
| Appearance |
Typically exists as solid at room temperature
|
| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
279.4±15.0 °C at 760 mmHg
|
| Melting Point |
5-7 °C(lit.)
|
| Flash Point |
122.1±11.1 °C
|
| Vapour Pressure |
0.0±0.3 mmHg at 25°C
|
| Index of Refraction |
1.559
|
| LogP |
4.9
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
0
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
14
|
| Complexity |
153
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CC1=CC(=CC=C1)C2=CC=CC(=C2)C
|
| InChi Key |
GVEDOIATHPCYGS-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C14H14/c1-11-5-3-7-13(9-11)14-8-4-6-12(2)10-14/h3-10H,1-2H3
|
| Chemical Name |
1-methyl-3-(3-methylphenyl)benzene
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.4867 mL | 27.4333 mL | 54.8667 mL | |
| 5 mM | 1.0973 mL | 5.4867 mL | 10.9733 mL | |
| 10 mM | 0.5487 mL | 2.7433 mL | 5.4867 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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