| Size | Price | Stock | Qty |
|---|---|---|---|
| 1mg |
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| 100mg | |||
| Other Sizes |
| Targets |
The biological target of 3-O-Acetyl-20-Hydroxyecdysone is not clearly defined in the provided sources. It is a steroid and may interact with steroid receptors or other cellular targets, but specific targets are not reported.
|
|---|---|
| ln Vitro |
Cell-free assays for 3-O-Acetyl-20-Hydroxyecdysone are not standard. As a steroid, its activity could be assessed in receptor binding assays, but specific assays are not reported. Its chemical properties and stability may be studied. In vitro, the specific biological activities of 3-O-Acetyl-20-Hydroxyecdysone are not well-documented. As a derivative of 20-hydroxyecdysone, it may share some of its activities, but specific data is not provided.
|
| ln Vivo |
In vivo, the effects of 3-O-Acetyl-20-Hydroxyecdysone are not well-characterized. As a phytoecdysteroid derivative, it may have effects on growth and development, but specific studies are not reported.
|
| Enzyme Assay |
Standard protocols for characterizing steroids may apply. Its purity and identity are confirmed by HPLC. Its physicochemical properties, such as solubility and stability, may be determined.
|
| Cell Assay |
Cells could be treated with 3-O-Acetyl-20-Hydroxyecdysone to study its effects, but no specific assays are reported. Its activity could be assessed using general cell viability or gene expression assays.
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| Animal Protocol |
In vivo studies are not reported. As a natural product derivative, it may be studied in animal models, but specific data is not available in the provided search results.
|
| ADME/Pharmacokinetics |
Pharmacokinetic properties are not reported for 3-O-Acetyl-20-Hydroxyecdysone. As a steroid, its absorption, distribution, metabolism, and excretion would be of interest, but no data is available.
|
| Toxicity/Toxicokinetics |
Toxicological data for 3-O-Acetyl-20-Hydroxyecdysone is not available. As a research compound, its safety profile is not well-established.
|
| Additional Infomation |
According to reports, 20-hydroxyecdysone 3-acetate has been found in gentian, creeping ajuga, and other organisms with available data.
3-O-Acetyl-20-Hydroxyecdysone is a steroid isolated from a natural source. It is a research compound with potential biological activities. It is not an approved drug and is for research use only. |
| Molecular Formula |
C29H46O8
|
|---|---|
| Molecular Weight |
522.671
|
| Exact Mass |
522.319
|
| CAS # |
22961-68-8
|
| PubChem CID |
10951463
|
| Appearance |
Typically exists as solid at room temperature
|
| LogP |
2.424
|
| Hydrogen Bond Donor Count |
5
|
| Hydrogen Bond Acceptor Count |
8
|
| Rotatable Bond Count |
7
|
| Heavy Atom Count |
37
|
| Complexity |
975
|
| Defined Atom Stereocenter Count |
10
|
| SMILES |
C12(C([H])([H])C([H])([H])C3([H])C4(C([H])([H])[H])C([H])([H])C(O[H])([H])C(OC(=O)C([H])([H])[H])([H])C([H])([H])C4([H])C(=O)C([H])=C3C1(C(C(C2(C(C(C(C(C(O[H])(C([H])([H])[H])C([H])([H])[H])([H])[H])([H])[H])(O[H])[H])(O[H])C([H])([H])[H])[H])([H])[H])([H])[H])O[H])C([H])([H])[H]
|
| InChi Key |
UWFCFVQTAHITKV-OQQOFWQASA-N
|
| InChi Code |
InChI=1S/C29H46O8/c1-16(30)37-22-14-19-20(31)13-18-17(26(19,4)15-21(22)32)7-11-27(5)23(8-12-29(18,27)36)28(6,35)24(33)9-10-25(2,3)34/h13,17,19,21-24,32-36H,7-12,14-15H2,1-6H3/t17-,19-,21-,22+,23-,24+,26+,27+,28+,29+/m0/s1
|
| Chemical Name |
[(2S,3R,5R,9R,10R,13R,14S,17S)-2,14-dihydroxy-10,13-dimethyl-6-oxo-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.9133 mL | 9.5663 mL | 19.1325 mL | |
| 5 mM | 0.3827 mL | 1.9133 mL | 3.8265 mL | |
| 10 mM | 0.1913 mL | 0.9566 mL | 1.9133 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
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