| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
3-Methylcyclohex-2-en-1-ol does not have a pharmacological target in mammalian systems. Its biological activity is as an insect pheromone, specifically an anti-aggregation pheromone for bark beetles. It acts on the olfactory system of insects to modulate their behavior, but the specific receptor targets are not defined in the context of drug discovery.
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| ln Vitro |
In vitro activity for 3-Methylcyclohex-2-en-1-ol is not applicable in a pharmacological sense. Its activity is evaluated in behavioral assays with insects rather than in cell-based or biochemical assays. It is a volatile organic compound that is studied for its effects on insect behavior.
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| ln Vivo |
In vivo, 3-Methylcyclohex-2-en-1-ol acts as an anti-aggregation pheromone in insects, particularly bark beetles. It is used in research to study insect behavior and communication. It is not used as a therapeutic agent in humans or animals.
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| Enzyme Assay |
A cell-free assay for 3-Methylcyclohex-2-en-1-ol is not applicable as it is not an enzyme inhibitor or receptor ligand in a mammalian context. Its properties as a pheromone are studied in behavioral assays with live insects.
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| Cell Assay |
Cellular experiments for 3-Methylcyclohex-2-en-1-ol are not typical, as its activity is assessed in insect behavioral studies rather than in cell culture.
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| Animal Protocol |
In vivo animal experiments for 3-Methylcyclohex-2-en-1-ol typically involve behavioral assays with insects, such as bark beetles. The compound's anti-aggregation effects are studied by exposing insects to the pheromone and observing their behavior. Specific protocols are not detailed in the available sources.
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| ADME/Pharmacokinetics |
3-Methylcyclohex-2-en-1-ol is a volatile liquid with a density of 0.946 g/mL and a boiling point of 56 °C at 1 mmHg. Its pharmacokinetic properties are not relevant as it is not a therapeutic drug. It is a research chemical used in insect behavior studies.
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| Toxicity/Toxicokinetics |
Toxicity data for 3-Methylcyclohex-2-en-1-ol are not provided in the available sources. As a volatile organic compound, it should be handled with appropriate safety precautions. It is intended for research use only and not for human consumption.
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| Additional Infomation |
3-Methylcyclohex-2-en-1-ol (CAS: 21378-21-2) is an anti-insect aggregation pheromone extracted from Dendroctonus bark beetles. It is also known as Seudenol. The compound functions as a potent antiaggregative pheromone. Its molecular formula is C7H12O and its molecular weight is 112.17. It is a useful research chemical for studying insect behavior and pheromone communication. It is not a therapeutic drug.
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| Molecular Formula |
C7H12O
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|---|---|
| Molecular Weight |
112.16958
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| Exact Mass |
112.089
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| CAS # |
21378-21-2
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| PubChem CID |
89487
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| Appearance |
Typically exists as solid at room temperature
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| Density |
0.977g/cm3
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| Boiling Point |
199ºC at 760mmHg
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| Melting Point |
56 °C/1 mmHg (lit.)
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| Flash Point |
71.7ºC
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| Vapour Pressure |
0.0876mmHg at 25°C
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| Index of Refraction |
n20/D 1.484(lit.)
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| LogP |
1.477
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
0
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| Heavy Atom Count |
8
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| Complexity |
105
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CC1=CC(CCC1)O
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| InChi Key |
XNDZQQSKSQTQQD-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C7H12O/c1-6-3-2-4-7(8)5-6/h5,7-8H,2-4H2,1H3
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| Chemical Name |
3-methylcyclohex-2-en-1-ol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 8.9150 mL | 44.5752 mL | 89.1504 mL | |
| 5 mM | 1.7830 mL | 8.9150 mL | 17.8301 mL | |
| 10 mM | 0.8915 mL | 4.4575 mL | 8.9150 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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