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    Rivastigmine Tartrate (ENA713; SDZ-ENA 713)
    Rivastigmine Tartrate (ENA713; SDZ-ENA 713)

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V1189
    CAS #: 129101-54-8Purity ≥98%

    Description: Rivastigmine Tartrate (formerly ENA-713, SDZ-ENA 713; Exelon, Exelon Patch), the tartrate salt of rivastigmine, is a potent and reversible cholinesterase inhibitor used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease. It inhibits cholinesterase with an IC50 of 5.5 μM, and is used as a parasympathomimetic or cholinergic agent for the management of mild to moderate Alzheimer disease, Dementia, and Parkinson's Disease. Rivastigmine is a carbamate-derived reversible cholinesterase inhibitor that is selective for the central nervous system. It acts by covalently modifying a serine residue in the active site by carbamoylation, as it stabilizes or reduces the rate of decline in certain cognitive functions. 

    ReferencesJ Clin Neurol. 2011 Sep;7(3):137-42. 

    Related CAS: 194930-00-2 [(R)-Rivastigmine D6 tartrate]

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    Molecular Weight (MW)400.42 
    FormulaC14H22N2O2.C4H6O6 
    CAS No.129101-54-8 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 42 mg/mL (104.9 mM) 
    Water: 80 mg/mL (199.8 mM)  
    Ethanol: 80 mg/mL (199.8 mM) 
    Solubility (In vivo)

    hemical Name: (2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate

    InChi Key: GWHQHAUAXRMMOT-UHFFFAOYSA-N

    InChi Code: InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)

    SMILES Code: CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O

    SynonymsENA-713; ENA713; ENA 713; Rivastigmine Tartrate; SDZ-ENA 713; SDZ-ENA713; SDZ-ENA-713; Rivastigmine bitartrate.


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